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DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK

The mechanism underlying acute kidney injury (AKI) and AKI-to-Chronic kidney disease (CKD) transition remains unclear, but mitochondrial dysfunction may be a key driving factor. Literature reports suggest that dual-specificity phosphatase 1 (DUSP1) plays a critical role in maintaining mitochondrial...

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Detalles Bibliográficos
Autores principales: Shi, Lang, Zha, Hongchu, Pan, Zhou, Wang, Jiayi, Xia, Yao, Li, Huimin, Huang, Hua, Yue, Ruchi, Song, Zhixia, Zhu, Jiefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630453/
https://www.ncbi.nlm.nih.gov/pubmed/37935658
http://dx.doi.org/10.1038/s41419-023-06247-4