Cargando…
Machine learning approaches to study the structure-activity relationships of LpxC inhibitors
Antimicrobial resistance (AMR) has emerged as one of the global threats to human health in the 21st century. Drug discovery of inhibitors against novel targets rather than conventional bacterial targets has been considered an inevitable strategy for the growing threat of AMR infections. In this stud...
Autores principales: | Yu, Tianshi, Chong, Li Chuin, Nantasenamat, Chanin, Anuwongcharoen, Nuttapat, Piacham, Theeraphon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630528/ https://www.ncbi.nlm.nih.gov/pubmed/38023567 http://dx.doi.org/10.17179/excli2023-6356 |
Ejemplares similares
-
Machine Learning
Approaches to Investigate the Structure–Activity
Relationship of Angiotensin-Converting Enzyme Inhibitors
por: Yu, Tianshi, et al.
Publicado: (2023) -
Cheminformatic
Analysis and Machine Learning Modeling
to Investigate Androgen Receptor Antagonists to Combat Prostate Cancer
por: Yu, Tianshi, et al.
Publicado: (2023) -
Towards combating antibiotic resistance by exploring the quantitative structure-activity relationship of NDM-1 inhibitors
por: Yu, Tianshi, et al.
Publicado: (2022) -
Exploring the Chemical Space of CYP17A1 Inhibitors Using Cheminformatics and Machine Learning
por: Yu, Tianshi, et al.
Publicado: (2023) -
Interplay of Klebsiella pneumoniae
fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis
por: Mostafavi, Mina, et al.
Publicado: (2018)