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Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder leading to anovulatory infertility. Abnormalities in the central neuroendocrine system governed by gonadotropin-releasing hormone (GnRH) neurons might be related to ovarian dysfunction in PCOS, although the link in th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630624/ https://www.ncbi.nlm.nih.gov/pubmed/37898094 http://dx.doi.org/10.1016/j.ebiom.2023.104850 |