Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder leading to anovulatory infertility. Abnormalities in the central neuroendocrine system governed by gonadotropin-releasing hormone (GnRH) neurons might be related to ovarian dysfunction in PCOS, although the link in th...

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Detalles Bibliográficos
Autores principales: Silva, Mauro S.B., Decoster, Laurine, Delpouve, Gaspard, Lhomme, Tori, Ternier, Gaetan, Prevot, Vincent, Giacobini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630624/
https://www.ncbi.nlm.nih.gov/pubmed/37898094
http://dx.doi.org/10.1016/j.ebiom.2023.104850

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