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Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors

Synthetic cytokine receptors can modulate cellular functions based on an artificial ligand to avoid off-target and/or unspecific effects. However, ligands that can modulate receptor activity so far have not been used clinically because of unknown toxicity and immunity against the ligands. Here, we d...

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Detalles Bibliográficos
Autores principales:	Ettich, Julia, Wittich, Christoph, Moll, Jens M., Behnke, Kristina, Floss, Doreen M., Reiners, Jens, Christmann, Andreas, Lang, Philipp A., Smits, Sander H.J., Kolmar, Harald, Scheller, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630626/ https://www.ncbi.nlm.nih.gov/pubmed/37734558 http://dx.doi.org/10.1016/j.jbc.2023.105270

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