Cell surface GRP78-directed CAR-T cells are effective at treating human pancreatic cancer in preclinical models

Pancreatic cancer is a highly lethal solid malignancy with limited treatment options. Chimeric antigen receptor T (CAR-T) cell therapy has been successfully applied to treat hematological malignancies, but faces many challenges in solid tumors. One major challenge is the shortage of tumor-selective...

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Detalles Bibliográficos
Autores principales: Yuan, Yuncang, Fan, Jiawei, Liang, Dandan, Wang, Shijie, Luo, Xu, Zhu, Yongjie, Liu, Nan, Xiang, Tingxiu, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630660/
https://www.ncbi.nlm.nih.gov/pubmed/37897831
http://dx.doi.org/10.1016/j.tranon.2023.101803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630660/
https://www.ncbi.nlm.nih.gov/pubmed/37897831
http://dx.doi.org/10.1016/j.tranon.2023.101803

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