Cargando…

Integrated multiomic data analysis reveals the clinical significance of TXNIP and contributing to immune microenvironment in triple negative breast cancer

Triple negative breast cancer (TNBC) is a type of breast cancer with the worst clinical outcome. TNBC is not sensitive to typical endocrine therapy and targeted therapy. Thioredoxin interacting protein (TXNIP), known as a tumor suppressor, is related to oxidative stress and energy metabolism. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Han, Zhang, PeiHe, Hu, Xingming, Zhang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630669/ https://www.ncbi.nlm.nih.gov/pubmed/37897832 http://dx.doi.org/10.1016/j.tranon.2023.101808

Ejemplares similares

Identification of a novel mechanism for reversal of doxorubicin-induced chemotherapy resistance by TXNIP in triple-negative breast cancer via promoting reactive oxygen-mediated DNA damage
por: Chen, Yiting, et al.
Publicado: (2022)

Multiomics technologies for comprehensive tumor microenvironment analysis in triple-negative breast cancer under neoadjuvant chemotherapy
por: Wang, Gang, et al.
Publicado: (2023)

Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis
por: Bareche, Y, et al.
Publicado: (2018)

Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
por: Huang, Hao, et al.
Publicado: (2021)

Integrated single-cell multiomics reveals novel immune candidate markers for post-traumatic coagulopathy
por: Zheng, Ping, et al.
Publicado: (2023)

Multiomics integration reveals the effect of Orexin A on glioblastoma
por: Yang, Sha, et al.
Publicado: (2023)

Integrating Genomic Information with Tumor-Immune Microenvironment in Triple-Negative Breast Cancer
por: Otohinoyi, David, et al.
Publicado: (2022)

Role of tumor microenvironment in triple-negative breast cancer and its prognostic significance
por: Yu, Tianjian, et al.
Publicado: (2017)

Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors
por: Tang, Xiaojia, et al.
Publicado: (2023)

Multiomics characteristics of neurogenesis-related gene are dysregulated in tumor immune microenvironment
por: Wang, Ben, et al.
Publicado: (2021)

Multiomics analysis reveals CT83 is the most specific gene for triple negative breast cancer and its hypomethylation is oncogenic in breast cancer
por: Chen, Chen, et al.
Publicado: (2021)

An Immune-Related Gene Prognostic Index for Triple-Negative Breast Cancer Integrates Multiple Aspects of Tumor-Immune Microenvironment
por: Wang, Xiaowei, et al.
Publicado: (2021)

Embracing Integrative Multiomics Approaches
por: Rotroff, Daniel M., et al.
Publicado: (2016)

Integrated Bioinformatics Data Analysis Reveals Prognostic Significance Of SIDT1 In Triple-Negative Breast Cancer
por: Wang, Ya, et al.
Publicado: (2019)

Multiomic analysis of cohesin reveals that ZBTB transcription factors contribute to chromatin interactions
por: Wang, Rui, et al.
Publicado: (2023)

Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
por: Patwa, Aalok, et al.
Publicado: (2021)

Integrated spatial multiomics reveals fibroblast fate during tissue repair
por: Foster, Deshka S., et al.
Publicado: (2021)

Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma
por: Jin, Zhipeng, et al.
Publicado: (2022)

Integrated Multiomics Analyses Revealing Different Molecular Profiles Between Early- and Late-Stage Lung Adenocarcinoma
por: Yue, Dongsheng, et al.
Publicado: (2021)

Multiomics integration of 22 immune-mediated monogenic diseases reveals an emergent axis of human immune health
por: Sparks, Rachel, et al.
Publicado: (2023)

Multiomics Analysis Reveals Aberrant Metabolism and Immunity Linked Gut Microbiota with Insomnia
por: Wang, Qinghua, et al.
Publicado: (2022)

Significance of the multiomics approach to elucidate disease mechanisms in humans
por: Fujio, Keishi
Publicado: (2022)

Prognostic Significance and Tumor Immune Microenvironment Heterogenicity of m5C RNA Methylation Regulators in Triple-Negative Breast Cancer
por: Huang, Zhidong, et al.
Publicado: (2021)

Spatially-resolved quantification of proteins in triple negative breast cancers reveals differences in the immune microenvironment associated with prognosis
por: Stewart, Rachel L., et al.
Publicado: (2020)

BSCI-09. Multiomic single cell analysis reveals emerging principles of tumor immune microenvironment inherent to NSCLC brain metastases
por: Wen, Lei, et al.
Publicado: (2021)

TXNIP interaction with the Her-1/2 pathway contributes to overall survival in breast cancer
por: Nie, Weiwei, et al.
Publicado: (2014)

The Characteristics of Tumor Microenvironment in Triple Negative Breast Cancer
por: Fan, Yiqi, et al.
Publicado: (2022)

Crosstalk between triple negative breast cancer and microenvironment
por: Smrekar, Karly, et al.
Publicado: (2023)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Application of radiomics-based multiomics combinations in the tumor microenvironment and cancer prognosis
por: Kang, Wendi, et al.
Publicado: (2023)

Integrated tumor genomic and immune microenvironment analysis identifies predictive biomarkers associated with the efficacy of neoadjuvant therapy for triple‐negative breast cancer
por: Zhu, Yanhui, et al.
Publicado: (2022)

Multiomics integration-based molecular characterizations of COVID-19
por: Li, Chuan-Xing, et al.
Publicado: (2021)

How many diseases is triple negative breast cancer: the protagonism of the immune microenvironment
por: Saraiva, Diana P, et al.
Publicado: (2017)

Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas
por: Zhang, Qi, et al.
Publicado: (2019)

Revealing the pathogenic changes of PAH based on multiomics characteristics
por: Zhang, Li, et al.
Publicado: (2019)

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma
por: Murai, Hiroki, et al.
Publicado: (2023)

TNFRSF11B Suppresses Memory CD4+ T Cell Infiltration in the Colon Cancer Microenvironment: A Multiomics Integrative Analysis
por: Zhang, Jun-rong, et al.
Publicado: (2021)

Regulatory T cells are associated with the tumor immune microenvironment and immunotherapy response in triple-negative breast cancer
por: Huang, Pengfei, et al.
Publicado: (2023)

Multiomic Integration of Public Oncology Databases in Bioconductor
por: Ramos, Marcel, et al.
Publicado: (2020)

Executable Network Models of Integrated Multiomics Data
por: Palshikar, Mukta G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vmun9bmskb49vb3onhh4pv79vl