Cargando…

Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes

A comparative study of the hypoglycemic and hypotriglyceridemic effects of raw and pasteurized camel milk was conducted on the lipid profiles of six groups of male normal and diabetic Sprague–Dawley rats (age, 7–8 weeks, 5/group). The standard procedure to induce diabetes in rats was to administer a...

Descripción completa

Detalles Bibliográficos
Autores principales: Al‐Saffar, Amal M., Al‐Qattan, Nadia Y., Al‐Sughayer, Mona A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630804/
https://www.ncbi.nlm.nih.gov/pubmed/37970378
http://dx.doi.org/10.1002/fsn3.3672
_version_ 1785146040907726848
author Al‐Saffar, Amal M.
Al‐Qattan, Nadia Y.
Al‐Sughayer, Mona A.
author_facet Al‐Saffar, Amal M.
Al‐Qattan, Nadia Y.
Al‐Sughayer, Mona A.
author_sort Al‐Saffar, Amal M.
collection PubMed
description A comparative study of the hypoglycemic and hypotriglyceridemic effects of raw and pasteurized camel milk was conducted on the lipid profiles of six groups of male normal and diabetic Sprague–Dawley rats (age, 7–8 weeks, 5/group). The standard procedure to induce diabetes in rats was to administer a single intraperitoneal injection of streptozotocin (55 mg/kg, body weight). Rats with fasting blood glucose levels higher than 250 mg/dL were considered diabetics. Raw and pasteurized camel milk reduced blood glucose and triacylglycerol (TAG) levels in diabetic rats. Raw camel milk showed no significant effect on low‐density blood and lipoprotein cholesterol in diabetic rats. Contrarily, pasteurized camel milk significantly increased high‐density lipoprotein cholesterol in diabetic rats. Comparative analysis revealed camel milk with higher levels of lactose, vitamin C, and mono‐unsaturated fatty acids (MUFA) and lower levels of fat, protein, ω6:ω3 PUFA (poly‐unsaturated fatty acids), and index of atherogenicity than cow's milk. Experiments with cow's milk on rats were not carried out because of their characterized inexplicable traits. This novel study suggests that camel milk can be substituted for diabetic patients in place of cow's milk, assuring no side effects besides their effective hypoglycemic and hypotriglyceridemic qualities.
format Online
Article
Text
id pubmed-10630804
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-106308042023-11-15 Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes Al‐Saffar, Amal M. Al‐Qattan, Nadia Y. Al‐Sughayer, Mona A. Food Sci Nutr Original Articles A comparative study of the hypoglycemic and hypotriglyceridemic effects of raw and pasteurized camel milk was conducted on the lipid profiles of six groups of male normal and diabetic Sprague–Dawley rats (age, 7–8 weeks, 5/group). The standard procedure to induce diabetes in rats was to administer a single intraperitoneal injection of streptozotocin (55 mg/kg, body weight). Rats with fasting blood glucose levels higher than 250 mg/dL were considered diabetics. Raw and pasteurized camel milk reduced blood glucose and triacylglycerol (TAG) levels in diabetic rats. Raw camel milk showed no significant effect on low‐density blood and lipoprotein cholesterol in diabetic rats. Contrarily, pasteurized camel milk significantly increased high‐density lipoprotein cholesterol in diabetic rats. Comparative analysis revealed camel milk with higher levels of lactose, vitamin C, and mono‐unsaturated fatty acids (MUFA) and lower levels of fat, protein, ω6:ω3 PUFA (poly‐unsaturated fatty acids), and index of atherogenicity than cow's milk. Experiments with cow's milk on rats were not carried out because of their characterized inexplicable traits. This novel study suggests that camel milk can be substituted for diabetic patients in place of cow's milk, assuring no side effects besides their effective hypoglycemic and hypotriglyceridemic qualities. John Wiley and Sons Inc. 2023-09-08 /pmc/articles/PMC10630804/ /pubmed/37970378 http://dx.doi.org/10.1002/fsn3.3672 Text en © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Al‐Saffar, Amal M.
Al‐Qattan, Nadia Y.
Al‐Sughayer, Mona A.
Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title_full Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title_fullStr Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title_full_unstemmed Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title_short Characterizing camel milk constituents in the Sprague–Dawley rats' blood: A comparative profile with cow's milk attributes
title_sort characterizing camel milk constituents in the sprague–dawley rats' blood: a comparative profile with cow's milk attributes
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630804/
https://www.ncbi.nlm.nih.gov/pubmed/37970378
http://dx.doi.org/10.1002/fsn3.3672
work_keys_str_mv AT alsaffaramalm characterizingcamelmilkconstituentsinthespraguedawleyratsbloodacomparativeprofilewithcowsmilkattributes
AT alqattannadiay characterizingcamelmilkconstituentsinthespraguedawleyratsbloodacomparativeprofilewithcowsmilkattributes
AT alsughayermonaa characterizingcamelmilkconstituentsinthespraguedawleyratsbloodacomparativeprofilewithcowsmilkattributes