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Multi‐omic network analysis identified betacellulin as a novel target of omega‐3 fatty acid attenuation of western diet‐induced nonalcoholic steatohepatitis

Clinical and preclinical studies established that supplementing diets with ω3 polyunsaturated fatty acids (PUFA) can reduce hepatic dysfunction in nonalcoholic steatohepatitis (NASH) but molecular underpinnings of this action were elusive. Herein, we used multi‐omic network analysis that unveiled cr...

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Detalles Bibliográficos
Autores principales: Padiadpu, Jyothi, Garcia‐Jaramillo, Manuel, Newman, Nolan K, Pederson, Jacob W, Rodrigues, Richard, Li, Zhipeng, Singh, Sehajvir, Monnier, Philip, Trinchieri, Giorgio, Brown, Kevin, Dzutsev, Amiran K, Shulzhenko, Natalia, Jump, Donald B, Morgun, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630881/
https://www.ncbi.nlm.nih.gov/pubmed/37859621
http://dx.doi.org/10.15252/emmm.202318367

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