Single‐cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

Glioblastoma (GBM) remains the most malignant primary brain tumor, with a median survival rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive microenvironment are key factors contributing to the poor response rates of current therapeutic approaches. GBM‐associated macrophages (GAM...

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Detalles Bibliográficos
Autores principales: Finotto, Lise, Cole, Basiel, Giese, Wolfgang, Baumann, Elisabeth, Claeys, Annelies, Vanmechelen, Maxime, Decraene, Brecht, Derweduwe, Marleen, Dubroja Lakic, Nikolina, Shankar, Gautam, Nagathihalli Kantharaju, Madhu, Albrecht, Jan Philipp, Geudens, Ilse, Stanchi, Fabio, Ligon, Keith L, Boeckx, Bram, Lambrechts, Diether, Harrington, Kyle, Van Den Bosch, Ludo, De Vleeschouwer, Steven, De Smet, Frederik, Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630887/
https://www.ncbi.nlm.nih.gov/pubmed/37791581
http://dx.doi.org/10.15252/emmm.202318144

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