Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study

Aim: This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients & methods/materials: Patients were recruited at their initial diagnosis at two facilities within Hamad Medical Corporation...

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Autores principales: Mohammedain, Shahd A, Badran, Saif, Elzouki, AbdelNaser Y, Salim, Halla, Chalaby, Ayesha, Siddiqui, MYA, Hussein, Yehia Y, Rahim, Hanan Abdul, Thalib, Lukman, Alam, Mohammed Fasihul, Al-Badriyeh, Daoud, Al-Maadeed, Sumaya, Doi, Suhail AR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630949/
https://www.ncbi.nlm.nih.gov/pubmed/37970094
http://dx.doi.org/10.2217/fvl-2023-0036
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author Mohammedain, Shahd A
Badran, Saif
Elzouki, AbdelNaser Y
Salim, Halla
Chalaby, Ayesha
Siddiqui, MYA
Hussein, Yehia Y
Rahim, Hanan Abdul
Thalib, Lukman
Alam, Mohammed Fasihul
Al-Badriyeh, Daoud
Al-Maadeed, Sumaya
Doi, Suhail AR
author_facet Mohammedain, Shahd A
Badran, Saif
Elzouki, AbdelNaser Y
Salim, Halla
Chalaby, Ayesha
Siddiqui, MYA
Hussein, Yehia Y
Rahim, Hanan Abdul
Thalib, Lukman
Alam, Mohammed Fasihul
Al-Badriyeh, Daoud
Al-Maadeed, Sumaya
Doi, Suhail AR
author_sort Mohammedain, Shahd A
collection PubMed
description Aim: This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients & methods/materials: Patients were recruited at their initial diagnosis at two facilities within Hamad Medical Corporation in Qatar. 356 adults were included for analysis. Predictors for progression of COVID-19 were all measured at disease onset and first contact with the health system. Results: The C statistic was 83% (95% CI: 78%–87%) and the calibration plot showed that the model was well-calibrated. Conclusion: The published prognostic model for the progression of COVID-19 infection showed satisfactory discrimination and calibration and the model is easy to apply in clinical practice.d
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spelling pubmed-106309492023-11-15 Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study Mohammedain, Shahd A Badran, Saif Elzouki, AbdelNaser Y Salim, Halla Chalaby, Ayesha Siddiqui, MYA Hussein, Yehia Y Rahim, Hanan Abdul Thalib, Lukman Alam, Mohammed Fasihul Al-Badriyeh, Daoud Al-Maadeed, Sumaya Doi, Suhail AR Future Virol Research Article Aim: This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients & methods/materials: Patients were recruited at their initial diagnosis at two facilities within Hamad Medical Corporation in Qatar. 356 adults were included for analysis. Predictors for progression of COVID-19 were all measured at disease onset and first contact with the health system. Results: The C statistic was 83% (95% CI: 78%–87%) and the calibration plot showed that the model was well-calibrated. Conclusion: The published prognostic model for the progression of COVID-19 infection showed satisfactory discrimination and calibration and the model is easy to apply in clinical practice.d Future Medicine Ltd 2023-11-07 2023-10 /pmc/articles/PMC10630949/ /pubmed/37970094 http://dx.doi.org/10.2217/fvl-2023-0036 Text en © 2023 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Mohammedain, Shahd A
Badran, Saif
Elzouki, AbdelNaser Y
Salim, Halla
Chalaby, Ayesha
Siddiqui, MYA
Hussein, Yehia Y
Rahim, Hanan Abdul
Thalib, Lukman
Alam, Mohammed Fasihul
Al-Badriyeh, Daoud
Al-Maadeed, Sumaya
Doi, Suhail AR
Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title_full Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title_fullStr Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title_full_unstemmed Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title_short Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study
title_sort validation of a risk prediction model for covid-19: the peril prospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630949/
https://www.ncbi.nlm.nih.gov/pubmed/37970094
http://dx.doi.org/10.2217/fvl-2023-0036
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