Freeze-Induced Phase Transition and Local Pressure in a Phospholipid/Water System: Novel Insights Were Obtained from a Time/Temperature Resolved Synchrotron X-ray Diffraction Study

[Image: see text] Water-to-ice transformation results in a 10% increase in volume, which can have a significant impact on biopharmaceuticals during freeze–thaw cycles due to the mechanical stresses imparted by the growing ice crystals. Whether these stresses would contribute to the destabilization o...

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Detalles Bibliográficos
Autores principales: Rodrigues, Miguel A., Matsarskaia, Olga, Rego, Pedro, Geraldes, Vitor, Connor, Lauren E., Oswald, Iain D. H., Sztucki, Michael, Shalaev, Evgenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630958/
https://www.ncbi.nlm.nih.gov/pubmed/37889088
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630958/
https://www.ncbi.nlm.nih.gov/pubmed/37889088
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00657

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