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Freeze-Induced Phase Transition and Local Pressure in a Phospholipid/Water System: Novel Insights Were Obtained from a Time/Temperature Resolved Synchrotron X-ray Diffraction Study
[Image: see text] Water-to-ice transformation results in a 10% increase in volume, which can have a significant impact on biopharmaceuticals during freeze–thaw cycles due to the mechanical stresses imparted by the growing ice crystals. Whether these stresses would contribute to the destabilization o...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630958/ https://www.ncbi.nlm.nih.gov/pubmed/37889088 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00657 |