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Comprehensive mapping of exon junction complex binding sites reveals universal EJC deposition in Drosophila

BACKGROUND: The exon junction complex (EJC) is involved in most steps of the mRNA life cycle, ranging from splicing to nonsense-mediated mRNA decay (NMD). It is assembled by the splicing machinery onto mRNA in a sequence-independent manner. A fundamental open question is whether the EJC is deposited...

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Detalles Bibliográficos
Autores principales:	Morillo, Lucía, Paternina, Toni, Alasseur, Quentin, Genovesio, Auguste, Schwartz, Schraga, Le Hir, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630996/ https://www.ncbi.nlm.nih.gov/pubmed/37936138 http://dx.doi.org/10.1186/s12915-023-01749-1

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