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Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics
The tyrosine kinase inhibitor sunitinib is an effective first-line treatment for patients with advanced renal cell carcinoma (RCC). Hypothesizing that a functional read-out by mass spectrometry-based (phospho, p-)proteomics will identify predictive biomarkers for treatment outcome of sunitinib, tumo...
Autores principales: | van der Wijngaart, Hanneke, Beekhof, Robin, Knol, Jaco C., Henneman, Alex A., de Goeij-de Haas, Richard, Piersma, Sander R., Pham, Thang V., Jimenez, Connie R., Verheul, Henk M. W., Labots, Mariette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631096/ https://www.ncbi.nlm.nih.gov/pubmed/37940875 http://dx.doi.org/10.1186/s12014-023-09437-6 |
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