GCN5L1 regulates pulmonary surfactant production by modulating lamellar body biogenesis and trafficking in mouse alveolar epithelial cells

BACKGROUND: The pulmonary surfactant that lines the air–liquid surface within alveoli is a protein–lipid mixture essential for gas exchange. Surfactant lipids and proteins are synthesized and stored in the lamellar body (LB) before being secreted from alveolar type II (AT2) cells. The molecular and...

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Detalles Bibliográficos
Autores principales: Xu, Wenqin, Ma, Xiaocui, Wang, Qing, Ye, Jingjing, Wang, Nengqian, Ye, Zhenzhen, Chen, Tianbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631113/
https://www.ncbi.nlm.nih.gov/pubmed/37936104
http://dx.doi.org/10.1186/s11658-023-00506-0

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