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Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

BACKGROUND: Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. Due to drug resistance to radiotherapy and chemotherapy, mainly due to the existence of cancer stem cells (CSCs), some children still have a poor prognosis. Therefore, researchers have focused their att...

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Detalles Bibliográficos
Autores principales: Mi, Tao, Tan, Xiaojun, Wang, Zhang, Zhang, Zhaoxia, Jin, Liming, Wang, Jinkui, Li, Mujie, Wu, Xin, He, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631185/
https://www.ncbi.nlm.nih.gov/pubmed/37941038
http://dx.doi.org/10.1186/s40001-023-01493-w