Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position

The unexpected potential of micellar medium to achieve challenging β-selective direct arylation of (oligo)thiophenes is reported. Thanks to the use of a water/surfactant solution in combination with natural feedstock-derived undecanoic acid as an additive, this high-yielding C–H coupling could be pe...

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Autores principales: Hauk, Pascal, Mazan, Valérie, Gallou, Fabrice, Wencel-Delord, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631230/
https://www.ncbi.nlm.nih.gov/pubmed/37969587
http://dx.doi.org/10.1039/d3sc03708h
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author Hauk, Pascal
Mazan, Valérie
Gallou, Fabrice
Wencel-Delord, Joanna
author_facet Hauk, Pascal
Mazan, Valérie
Gallou, Fabrice
Wencel-Delord, Joanna
author_sort Hauk, Pascal
collection PubMed
description The unexpected potential of micellar medium to achieve challenging β-selective direct arylation of (oligo)thiophenes is reported. Thanks to the use of a water/surfactant solution in combination with natural feedstock-derived undecanoic acid as an additive, this high-yielding C–H coupling could be performed regioselectively at room temperature.
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spelling pubmed-106312302023-11-15 Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position Hauk, Pascal Mazan, Valérie Gallou, Fabrice Wencel-Delord, Joanna Chem Sci Chemistry The unexpected potential of micellar medium to achieve challenging β-selective direct arylation of (oligo)thiophenes is reported. Thanks to the use of a water/surfactant solution in combination with natural feedstock-derived undecanoic acid as an additive, this high-yielding C–H coupling could be performed regioselectively at room temperature. The Royal Society of Chemistry 2023-10-05 /pmc/articles/PMC10631230/ /pubmed/37969587 http://dx.doi.org/10.1039/d3sc03708h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Hauk, Pascal
Mazan, Valérie
Gallou, Fabrice
Wencel-Delord, Joanna
Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title_full Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title_fullStr Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title_full_unstemmed Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title_short Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position
title_sort micellar catalysis: a green solution to enable undirected and mild c–h activation of (oligo)thiophenes at the challenging β-position
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631230/
https://www.ncbi.nlm.nih.gov/pubmed/37969587
http://dx.doi.org/10.1039/d3sc03708h
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