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Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631233/ https://www.ncbi.nlm.nih.gov/pubmed/37969583 http://dx.doi.org/10.1039/d3sc02515b |
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author | Vyas, Ved Maurya, Priyanka Indra, Arindam |
author_facet | Vyas, Ved Maurya, Priyanka Indra, Arindam |
author_sort | Vyas, Ved |
collection | PubMed |
description | N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal based catalysts is required for large-scale applications. In this work, we have reported metal–organic framework-derived CoN(x)@NC catalysts for the selective N-alkylation of anilines with different types of alcohols. The Co–N coordination in CoN(x)@NC was found to be extremely important to improve the conversion efficiency and yield of the product. As a result, CoN(x)@NC produced 99% yield of the desired amines, which is far better than that of Co@C (yield = 65%). In addition, CoN(x)@NC showed remarkable recyclability for six cycles with a minimum drop in the yield of the desired product. |
format | Online Article Text |
id | pubmed-10631233 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-106312332023-11-15 Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline Vyas, Ved Maurya, Priyanka Indra, Arindam Chem Sci Chemistry N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal based catalysts is required for large-scale applications. In this work, we have reported metal–organic framework-derived CoN(x)@NC catalysts for the selective N-alkylation of anilines with different types of alcohols. The Co–N coordination in CoN(x)@NC was found to be extremely important to improve the conversion efficiency and yield of the product. As a result, CoN(x)@NC produced 99% yield of the desired amines, which is far better than that of Co@C (yield = 65%). In addition, CoN(x)@NC showed remarkable recyclability for six cycles with a minimum drop in the yield of the desired product. The Royal Society of Chemistry 2023-10-09 /pmc/articles/PMC10631233/ /pubmed/37969583 http://dx.doi.org/10.1039/d3sc02515b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Vyas, Ved Maurya, Priyanka Indra, Arindam Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title | Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title_full | Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title_fullStr | Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title_full_unstemmed | Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title_short | Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline |
title_sort | metal–organic framework-derived con(x) nanoparticles on n-doped carbon for selective n-alkylation of aniline |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631233/ https://www.ncbi.nlm.nih.gov/pubmed/37969583 http://dx.doi.org/10.1039/d3sc02515b |
work_keys_str_mv | AT vyasved metalorganicframeworkderivedconxnanoparticlesonndopedcarbonforselectivenalkylationofaniline AT mauryapriyanka metalorganicframeworkderivedconxnanoparticlesonndopedcarbonforselectivenalkylationofaniline AT indraarindam metalorganicframeworkderivedconxnanoparticlesonndopedcarbonforselectivenalkylationofaniline |