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Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline

N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal...

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Autores principales: Vyas, Ved, Maurya, Priyanka, Indra, Arindam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631233/
https://www.ncbi.nlm.nih.gov/pubmed/37969583
http://dx.doi.org/10.1039/d3sc02515b
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author Vyas, Ved
Maurya, Priyanka
Indra, Arindam
author_facet Vyas, Ved
Maurya, Priyanka
Indra, Arindam
author_sort Vyas, Ved
collection PubMed
description N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal based catalysts is required for large-scale applications. In this work, we have reported metal–organic framework-derived CoN(x)@NC catalysts for the selective N-alkylation of anilines with different types of alcohols. The Co–N coordination in CoN(x)@NC was found to be extremely important to improve the conversion efficiency and yield of the product. As a result, CoN(x)@NC produced 99% yield of the desired amines, which is far better than that of Co@C (yield = 65%). In addition, CoN(x)@NC showed remarkable recyclability for six cycles with a minimum drop in the yield of the desired product.
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spelling pubmed-106312332023-11-15 Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline Vyas, Ved Maurya, Priyanka Indra, Arindam Chem Sci Chemistry N-alkylation of anilines by alcohols can be used as an efficient strategy to synthesise a wide range of secondary amines. In this respect, a hydrogen borrowing methodology has been explored using precious metal-based catalysts. However, the utilisation of cheap and readily available transition metal based catalysts is required for large-scale applications. In this work, we have reported metal–organic framework-derived CoN(x)@NC catalysts for the selective N-alkylation of anilines with different types of alcohols. The Co–N coordination in CoN(x)@NC was found to be extremely important to improve the conversion efficiency and yield of the product. As a result, CoN(x)@NC produced 99% yield of the desired amines, which is far better than that of Co@C (yield = 65%). In addition, CoN(x)@NC showed remarkable recyclability for six cycles with a minimum drop in the yield of the desired product. The Royal Society of Chemistry 2023-10-09 /pmc/articles/PMC10631233/ /pubmed/37969583 http://dx.doi.org/10.1039/d3sc02515b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Vyas, Ved
Maurya, Priyanka
Indra, Arindam
Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title_full Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title_fullStr Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title_full_unstemmed Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title_short Metal–organic framework-derived CoN(x) nanoparticles on N-doped carbon for selective N-alkylation of aniline
title_sort metal–organic framework-derived con(x) nanoparticles on n-doped carbon for selective n-alkylation of aniline
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631233/
https://www.ncbi.nlm.nih.gov/pubmed/37969583
http://dx.doi.org/10.1039/d3sc02515b
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AT indraarindam metalorganicframeworkderivedconxnanoparticlesonndopedcarbonforselectivenalkylationofaniline