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Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence-based prediction, expert evaluation, clinical corroboration and mechanism of action analyses
BACKGROUND AND AIMS: Cocaine use disorder (CUD) is a significant public health issue for which there is no Food and Drug Administration (FDA) approved medication. Drug repurposing looks for new cost-effective uses of approved drugs. This study presents an integrated strategy to identify repurposed F...
Autores principales: | Gao, Zhenxiang, Winhusen, T. John, Gorenflo, Maria, Ghitza, Udi E., Davis, Pamela B., Kaelber, David C., Xu, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631254/ https://www.ncbi.nlm.nih.gov/pubmed/36792381 http://dx.doi.org/10.1111/add.16168 |
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