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The Liver Tumor Segmentation Benchmark (LiTS)

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention...

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Autores principales: Bilic, Patrick, Christ, Patrick, Li, Hongwei Bran, Vorontsov, Eugene, Ben-Cohen, Avi, Kaissis, Georgios, Szeskin, Adi, Jacobs, Colin, Mamani, Gabriel Efrain Humpire, Chartrand, Gabriel, Lohöfer, Fabian, Holch, Julian Walter, Sommer, Wieland, Hofmann, Felix, Hostettler, Alexandre, Lev-Cohain, Naama, Drozdzal, Michal, Amitai, Michal Marianne, Vivanti, Refael, Sosna, Jacob, Ezhov, Ivan, Sekuboyina, Anjany, Navarro, Fernando, Kofler, Florian, Paetzold, Johannes C., Shit, Suprosanna, Hu, Xiaobin, Lipková, Jana, Rempfler, Markus, Piraud, Marie, Kirschke, Jan, Wiestler, Benedikt, Zhang, Zhiheng, Hülsemeyer, Christian, Beetz, Marcel, Ettlinger, Florian, Antonelli, Michela, Bae, Woong, Bellver, Míriam, Bi, Lei, Chen, Hao, Chlebus, Grzegorz, Dam, Erik B., Dou, Qi, Fu, Chi-Wing, Georgescu, Bogdan, Giró-i-Nieto, Xavier, Gruen, Felix, Han, Xu, Heng, Pheng-Ann, Hesser, Jürgen, Moltz, Jan Hendrik, Igel, Christian, Isensee, Fabian, Jäger, Paul, Jia, Fucang, Kaluva, Krishna Chaitanya, Khened, Mahendra, Kim, Ildoo, Kim, Jae-Hun, Kim, Sungwoong, Kohl, Simon, Konopczynski, Tomasz, Kori, Avinash, Krishnamurthi, Ganapathy, Li, Fan, Li, Hongchao, Li, Junbo, Li, Xiaomeng, Lowengrub, John, Ma, Jun, Maier-Hein, Klaus, Maninis, Kevis-Kokitsi, Meine, Hans, Merhof, Dorit, Pai, Akshay, Perslev, Mathias, Petersen, Jens, Pont-Tuset, Jordi, Qi, Jin, Qi, Xiaojuan, Rippel, Oliver, Roth, Karsten, Sarasua, Ignacio, Schenk, Andrea, Shen, Zengming, Torres, Jordi, Wachinger, Christian, Wang, Chunliang, Weninger, Leon, Wu, Jianrong, Xu, Daguang, Yang, Xiaoping, Yu, Simon Chun-Ho, Yuan, Yading, Yue, Miao, Zhang, Liping, Cardoso, Jorge, Bakas, Spyridon, Braren, Rickmer, Heinemann, Volker, Pal, Christopher, Tang, An, Kadoury, Samuel, Soler, Luc, van Ginneken, Bram, Greenspan, Hayit, Joskowicz, Leo, Menze, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631490/
https://www.ncbi.nlm.nih.gov/pubmed/36481607
http://dx.doi.org/10.1016/j.media.2022.102680
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author Bilic, Patrick
Christ, Patrick
Li, Hongwei Bran
Vorontsov, Eugene
Ben-Cohen, Avi
Kaissis, Georgios
Szeskin, Adi
Jacobs, Colin
Mamani, Gabriel Efrain Humpire
Chartrand, Gabriel
Lohöfer, Fabian
Holch, Julian Walter
Sommer, Wieland
Hofmann, Felix
Hostettler, Alexandre
Lev-Cohain, Naama
Drozdzal, Michal
Amitai, Michal Marianne
Vivanti, Refael
Sosna, Jacob
Ezhov, Ivan
Sekuboyina, Anjany
Navarro, Fernando
Kofler, Florian
Paetzold, Johannes C.
Shit, Suprosanna
Hu, Xiaobin
Lipková, Jana
Rempfler, Markus
Piraud, Marie
Kirschke, Jan
Wiestler, Benedikt
Zhang, Zhiheng
Hülsemeyer, Christian
Beetz, Marcel
Ettlinger, Florian
Antonelli, Michela
Bae, Woong
Bellver, Míriam
Bi, Lei
Chen, Hao
Chlebus, Grzegorz
Dam, Erik B.
Dou, Qi
Fu, Chi-Wing
Georgescu, Bogdan
Giró-i-Nieto, Xavier
Gruen, Felix
Han, Xu
Heng, Pheng-Ann
Hesser, Jürgen
Moltz, Jan Hendrik
Igel, Christian
Isensee, Fabian
Jäger, Paul
Jia, Fucang
Kaluva, Krishna Chaitanya
Khened, Mahendra
Kim, Ildoo
Kim, Jae-Hun
Kim, Sungwoong
Kohl, Simon
Konopczynski, Tomasz
Kori, Avinash
Krishnamurthi, Ganapathy
Li, Fan
Li, Hongchao
Li, Junbo
Li, Xiaomeng
Lowengrub, John
Ma, Jun
Maier-Hein, Klaus
Maninis, Kevis-Kokitsi
Meine, Hans
Merhof, Dorit
Pai, Akshay
Perslev, Mathias
Petersen, Jens
Pont-Tuset, Jordi
Qi, Jin
Qi, Xiaojuan
Rippel, Oliver
Roth, Karsten
Sarasua, Ignacio
Schenk, Andrea
Shen, Zengming
Torres, Jordi
Wachinger, Christian
Wang, Chunliang
Weninger, Leon
Wu, Jianrong
Xu, Daguang
Yang, Xiaoping
Yu, Simon Chun-Ho
Yuan, Yading
Yue, Miao
Zhang, Liping
Cardoso, Jorge
Bakas, Spyridon
Braren, Rickmer
Heinemann, Volker
Pal, Christopher
Tang, An
Kadoury, Samuel
Soler, Luc
van Ginneken, Bram
Greenspan, Hayit
Joskowicz, Leo
Menze, Bjoern
author_facet Bilic, Patrick
Christ, Patrick
Li, Hongwei Bran
Vorontsov, Eugene
Ben-Cohen, Avi
Kaissis, Georgios
Szeskin, Adi
Jacobs, Colin
Mamani, Gabriel Efrain Humpire
Chartrand, Gabriel
Lohöfer, Fabian
Holch, Julian Walter
Sommer, Wieland
Hofmann, Felix
Hostettler, Alexandre
Lev-Cohain, Naama
Drozdzal, Michal
Amitai, Michal Marianne
Vivanti, Refael
Sosna, Jacob
Ezhov, Ivan
Sekuboyina, Anjany
Navarro, Fernando
Kofler, Florian
Paetzold, Johannes C.
Shit, Suprosanna
Hu, Xiaobin
Lipková, Jana
Rempfler, Markus
Piraud, Marie
Kirschke, Jan
Wiestler, Benedikt
Zhang, Zhiheng
Hülsemeyer, Christian
Beetz, Marcel
Ettlinger, Florian
Antonelli, Michela
Bae, Woong
Bellver, Míriam
Bi, Lei
Chen, Hao
Chlebus, Grzegorz
Dam, Erik B.
Dou, Qi
Fu, Chi-Wing
Georgescu, Bogdan
Giró-i-Nieto, Xavier
Gruen, Felix
Han, Xu
Heng, Pheng-Ann
Hesser, Jürgen
Moltz, Jan Hendrik
Igel, Christian
Isensee, Fabian
Jäger, Paul
Jia, Fucang
Kaluva, Krishna Chaitanya
Khened, Mahendra
Kim, Ildoo
Kim, Jae-Hun
Kim, Sungwoong
Kohl, Simon
Konopczynski, Tomasz
Kori, Avinash
Krishnamurthi, Ganapathy
Li, Fan
Li, Hongchao
Li, Junbo
Li, Xiaomeng
Lowengrub, John
Ma, Jun
Maier-Hein, Klaus
Maninis, Kevis-Kokitsi
Meine, Hans
Merhof, Dorit
Pai, Akshay
Perslev, Mathias
Petersen, Jens
Pont-Tuset, Jordi
Qi, Jin
Qi, Xiaojuan
Rippel, Oliver
Roth, Karsten
Sarasua, Ignacio
Schenk, Andrea
Shen, Zengming
Torres, Jordi
Wachinger, Christian
Wang, Chunliang
Weninger, Leon
Wu, Jianrong
Xu, Daguang
Yang, Xiaoping
Yu, Simon Chun-Ho
Yuan, Yading
Yue, Miao
Zhang, Liping
Cardoso, Jorge
Bakas, Spyridon
Braren, Rickmer
Heinemann, Volker
Pal, Christopher
Tang, An
Kadoury, Samuel
Soler, Luc
van Ginneken, Bram
Greenspan, Hayit
Joskowicz, Leo
Menze, Bjoern
author_sort Bilic, Patrick
collection PubMed
description In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper−/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via https://competitions.codalab.org/competitions/17094.
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spelling pubmed-106314902023-11-07 The Liver Tumor Segmentation Benchmark (LiTS) Bilic, Patrick Christ, Patrick Li, Hongwei Bran Vorontsov, Eugene Ben-Cohen, Avi Kaissis, Georgios Szeskin, Adi Jacobs, Colin Mamani, Gabriel Efrain Humpire Chartrand, Gabriel Lohöfer, Fabian Holch, Julian Walter Sommer, Wieland Hofmann, Felix Hostettler, Alexandre Lev-Cohain, Naama Drozdzal, Michal Amitai, Michal Marianne Vivanti, Refael Sosna, Jacob Ezhov, Ivan Sekuboyina, Anjany Navarro, Fernando Kofler, Florian Paetzold, Johannes C. Shit, Suprosanna Hu, Xiaobin Lipková, Jana Rempfler, Markus Piraud, Marie Kirschke, Jan Wiestler, Benedikt Zhang, Zhiheng Hülsemeyer, Christian Beetz, Marcel Ettlinger, Florian Antonelli, Michela Bae, Woong Bellver, Míriam Bi, Lei Chen, Hao Chlebus, Grzegorz Dam, Erik B. Dou, Qi Fu, Chi-Wing Georgescu, Bogdan Giró-i-Nieto, Xavier Gruen, Felix Han, Xu Heng, Pheng-Ann Hesser, Jürgen Moltz, Jan Hendrik Igel, Christian Isensee, Fabian Jäger, Paul Jia, Fucang Kaluva, Krishna Chaitanya Khened, Mahendra Kim, Ildoo Kim, Jae-Hun Kim, Sungwoong Kohl, Simon Konopczynski, Tomasz Kori, Avinash Krishnamurthi, Ganapathy Li, Fan Li, Hongchao Li, Junbo Li, Xiaomeng Lowengrub, John Ma, Jun Maier-Hein, Klaus Maninis, Kevis-Kokitsi Meine, Hans Merhof, Dorit Pai, Akshay Perslev, Mathias Petersen, Jens Pont-Tuset, Jordi Qi, Jin Qi, Xiaojuan Rippel, Oliver Roth, Karsten Sarasua, Ignacio Schenk, Andrea Shen, Zengming Torres, Jordi Wachinger, Christian Wang, Chunliang Weninger, Leon Wu, Jianrong Xu, Daguang Yang, Xiaoping Yu, Simon Chun-Ho Yuan, Yading Yue, Miao Zhang, Liping Cardoso, Jorge Bakas, Spyridon Braren, Rickmer Heinemann, Volker Pal, Christopher Tang, An Kadoury, Samuel Soler, Luc van Ginneken, Bram Greenspan, Hayit Joskowicz, Leo Menze, Bjoern Med Image Anal Article In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper−/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via https://competitions.codalab.org/competitions/17094. 2023-02 2022-11-17 /pmc/articles/PMC10631490/ /pubmed/36481607 http://dx.doi.org/10.1016/j.media.2022.102680 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Article
Bilic, Patrick
Christ, Patrick
Li, Hongwei Bran
Vorontsov, Eugene
Ben-Cohen, Avi
Kaissis, Georgios
Szeskin, Adi
Jacobs, Colin
Mamani, Gabriel Efrain Humpire
Chartrand, Gabriel
Lohöfer, Fabian
Holch, Julian Walter
Sommer, Wieland
Hofmann, Felix
Hostettler, Alexandre
Lev-Cohain, Naama
Drozdzal, Michal
Amitai, Michal Marianne
Vivanti, Refael
Sosna, Jacob
Ezhov, Ivan
Sekuboyina, Anjany
Navarro, Fernando
Kofler, Florian
Paetzold, Johannes C.
Shit, Suprosanna
Hu, Xiaobin
Lipková, Jana
Rempfler, Markus
Piraud, Marie
Kirschke, Jan
Wiestler, Benedikt
Zhang, Zhiheng
Hülsemeyer, Christian
Beetz, Marcel
Ettlinger, Florian
Antonelli, Michela
Bae, Woong
Bellver, Míriam
Bi, Lei
Chen, Hao
Chlebus, Grzegorz
Dam, Erik B.
Dou, Qi
Fu, Chi-Wing
Georgescu, Bogdan
Giró-i-Nieto, Xavier
Gruen, Felix
Han, Xu
Heng, Pheng-Ann
Hesser, Jürgen
Moltz, Jan Hendrik
Igel, Christian
Isensee, Fabian
Jäger, Paul
Jia, Fucang
Kaluva, Krishna Chaitanya
Khened, Mahendra
Kim, Ildoo
Kim, Jae-Hun
Kim, Sungwoong
Kohl, Simon
Konopczynski, Tomasz
Kori, Avinash
Krishnamurthi, Ganapathy
Li, Fan
Li, Hongchao
Li, Junbo
Li, Xiaomeng
Lowengrub, John
Ma, Jun
Maier-Hein, Klaus
Maninis, Kevis-Kokitsi
Meine, Hans
Merhof, Dorit
Pai, Akshay
Perslev, Mathias
Petersen, Jens
Pont-Tuset, Jordi
Qi, Jin
Qi, Xiaojuan
Rippel, Oliver
Roth, Karsten
Sarasua, Ignacio
Schenk, Andrea
Shen, Zengming
Torres, Jordi
Wachinger, Christian
Wang, Chunliang
Weninger, Leon
Wu, Jianrong
Xu, Daguang
Yang, Xiaoping
Yu, Simon Chun-Ho
Yuan, Yading
Yue, Miao
Zhang, Liping
Cardoso, Jorge
Bakas, Spyridon
Braren, Rickmer
Heinemann, Volker
Pal, Christopher
Tang, An
Kadoury, Samuel
Soler, Luc
van Ginneken, Bram
Greenspan, Hayit
Joskowicz, Leo
Menze, Bjoern
The Liver Tumor Segmentation Benchmark (LiTS)
title The Liver Tumor Segmentation Benchmark (LiTS)
title_full The Liver Tumor Segmentation Benchmark (LiTS)
title_fullStr The Liver Tumor Segmentation Benchmark (LiTS)
title_full_unstemmed The Liver Tumor Segmentation Benchmark (LiTS)
title_short The Liver Tumor Segmentation Benchmark (LiTS)
title_sort liver tumor segmentation benchmark (lits)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631490/
https://www.ncbi.nlm.nih.gov/pubmed/36481607
http://dx.doi.org/10.1016/j.media.2022.102680
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