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SOX1 Antibody in a Patient With Serotonin Syndrome

SOX1 antibody is an autoimmune antibody, usually associated with Lambert-Eaton myasthenic syndrome, paraneoplastic conditions, and encephalitis. This antibody has also been found among psychiatric patients. However, the role of SOX1 antibody in serotonin syndrome has not yet been defined, as a liter...

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Autores principales: Hoffer, Julia, Frem, William, Alkana, Jessica, Chih, Charisse, Liu, Antonio K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631746/
https://www.ncbi.nlm.nih.gov/pubmed/37946854
http://dx.doi.org/10.7759/cureus.48516
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author Hoffer, Julia
Frem, William
Alkana, Jessica
Chih, Charisse
Liu, Antonio K
author_facet Hoffer, Julia
Frem, William
Alkana, Jessica
Chih, Charisse
Liu, Antonio K
author_sort Hoffer, Julia
collection PubMed
description SOX1 antibody is an autoimmune antibody, usually associated with Lambert-Eaton myasthenic syndrome, paraneoplastic conditions, and encephalitis. This antibody has also been found among psychiatric patients. However, the role of SOX1 antibody in serotonin syndrome has not yet been defined, as a literature search yielded no results. Therefore, the treatment as such has unknown clinical significance. In this case study, we report a patient with SOX1 antibodies and altered mental status out of proportion to serotonin syndrome whose symptoms improved with simultaneous treatment of both conditions.
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spelling pubmed-106317462023-11-09 SOX1 Antibody in a Patient With Serotonin Syndrome Hoffer, Julia Frem, William Alkana, Jessica Chih, Charisse Liu, Antonio K Cureus Neurology SOX1 antibody is an autoimmune antibody, usually associated with Lambert-Eaton myasthenic syndrome, paraneoplastic conditions, and encephalitis. This antibody has also been found among psychiatric patients. However, the role of SOX1 antibody in serotonin syndrome has not yet been defined, as a literature search yielded no results. Therefore, the treatment as such has unknown clinical significance. In this case study, we report a patient with SOX1 antibodies and altered mental status out of proportion to serotonin syndrome whose symptoms improved with simultaneous treatment of both conditions. Cureus 2023-11-08 /pmc/articles/PMC10631746/ /pubmed/37946854 http://dx.doi.org/10.7759/cureus.48516 Text en Copyright © 2023, Hoffer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Hoffer, Julia
Frem, William
Alkana, Jessica
Chih, Charisse
Liu, Antonio K
SOX1 Antibody in a Patient With Serotonin Syndrome
title SOX1 Antibody in a Patient With Serotonin Syndrome
title_full SOX1 Antibody in a Patient With Serotonin Syndrome
title_fullStr SOX1 Antibody in a Patient With Serotonin Syndrome
title_full_unstemmed SOX1 Antibody in a Patient With Serotonin Syndrome
title_short SOX1 Antibody in a Patient With Serotonin Syndrome
title_sort sox1 antibody in a patient with serotonin syndrome
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631746/
https://www.ncbi.nlm.nih.gov/pubmed/37946854
http://dx.doi.org/10.7759/cureus.48516
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