The apelin-apelin receptor signaling pathway in fibroblasts is involved in tumor growth via p53 expression of cancer cells

Cancer-associated fibroblasts (CAFs) are pivotal in tumor progression. TP53-deficiency in cancer cells is associated with robust stromal activation. The apelin-apelin receptor (APJ) system has been implicated in suppressing fibroblast-to-myofibroblast transition in non-neoplastic organ fibrosis. The...

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Detalles Bibliográficos
Autores principales: Saiki, Hirotsugu, Hayashi, Yoshito, Yoshii, Shunsuke, Kimura, Eiji, Nakagawa, Kentaro, Kato, Minoru, Uema, Ryotaro, Inoue, Takanori, Sakatani, Akihiko, Yoshihara, Takeo, Tsujii, Yoshiki, Shinzaki, Shinichiro, Iijima, Hideki, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631769/
https://www.ncbi.nlm.nih.gov/pubmed/37921070
http://dx.doi.org/10.3892/ijo.2023.5587

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