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Development and validation of a bioanalytical assay for the measurement of total and unbound teicoplanin in human serum

BACKGROUND: The glycopeptide teicoplanin is considered first-line treatment for severe infections caused by Gram-positive bacteria. Individualized treatment of teicoplanin is gaining interest. As only protein-unbound drug is pharmacologically active, a sensitive assay measuring unbound and total tei...

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Detalles Bibliográficos
Autores principales:	Mouton, J W A, Raaijmakers, J, Botterblom, M, Toonen, M, ter Heine, R, Smeets, R L, Brüggemann, R J M, te Brake, L, Jager, N G L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631822/ https://www.ncbi.nlm.nih.gov/pubmed/37757461 http://dx.doi.org/10.1093/jac/dkad290

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