Population pharmacokinetics of a combination of miltefosine and paromomycin in Eastern African children and adults with visceral leishmaniasis

OBJECTIVES: To improve visceral leishmaniasis (VL) treatment in Eastern Africa, 14- and 28-day combination regimens of paromomycin plus allometrically dosed miltefosine were evaluated. As the majority of patients affected by VL are children, adequate paediatric exposure to miltefosine and paromomyci...

Descripción completa

Detalles Bibliográficos
Autores principales: Verrest, Luka, Roseboom, Ignace C, Wasunna, Monique, Mbui, Jane, Njenga, Simon, Musa, Ahmed M, Olobo, Joseph, Mohammed, Rezika, Ritmeijer, Koert, Chu, Wan-Yu, Huitema, Alwin D R, Solomos, Alexandra, Alves, Fabiana, Dorlo, Thomas P C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631828/
https://www.ncbi.nlm.nih.gov/pubmed/37726401
http://dx.doi.org/10.1093/jac/dkad286

Ejemplares similares

Ejemplares similares