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Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion

BACKGROUND: We present the case of a patient who presents with a high velocity thoracoabdominal gunshot wound requiring ultramassive transfusion who exhausted the county blood bank requiring adjunctive therapies to balanced blood product transfusion while additional blood products could be obtained....

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Autores principales: Jackson, Max, Berman, Spencer, Rueda, Mario, Borrego, Robert, Lottenberg, Lawrence, Azar, Faris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632100/
https://www.ncbi.nlm.nih.gov/pubmed/37955000
http://dx.doi.org/10.1016/j.tcr.2023.100955
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author Jackson, Max
Berman, Spencer
Rueda, Mario
Borrego, Robert
Lottenberg, Lawrence
Azar, Faris
author_facet Jackson, Max
Berman, Spencer
Rueda, Mario
Borrego, Robert
Lottenberg, Lawrence
Azar, Faris
author_sort Jackson, Max
collection PubMed
description BACKGROUND: We present the case of a patient who presents with a high velocity thoracoabdominal gunshot wound requiring ultramassive transfusion who exhausted the county blood bank requiring adjunctive therapies to balanced blood product transfusion while additional blood products could be obtained. SUMMARY: Thoracoabdominal gunshot wounds carry a high mortality of 14–37 % because of the risk to produce cardiopulmonary, solid organ as well as major vascular injuries (Mandal and Oparah (1989) [1]). Ultramassive transfusion (>20 units of blood product transfusion) also carries high morbidity and mortality and management has generally centered on balanced transfusion (Matthay et al. (2021) [2]). CONCLUSION: Balanced blood product transfusion reduces mortality for patients requiring ultramassive transfusion but when this is not possible utilization of adjuncts to blood products may temporize resuscitation until additional blood products can be obtained.
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spelling pubmed-106321002023-11-10 Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion Jackson, Max Berman, Spencer Rueda, Mario Borrego, Robert Lottenberg, Lawrence Azar, Faris Trauma Case Rep Case Report BACKGROUND: We present the case of a patient who presents with a high velocity thoracoabdominal gunshot wound requiring ultramassive transfusion who exhausted the county blood bank requiring adjunctive therapies to balanced blood product transfusion while additional blood products could be obtained. SUMMARY: Thoracoabdominal gunshot wounds carry a high mortality of 14–37 % because of the risk to produce cardiopulmonary, solid organ as well as major vascular injuries (Mandal and Oparah (1989) [1]). Ultramassive transfusion (>20 units of blood product transfusion) also carries high morbidity and mortality and management has generally centered on balanced transfusion (Matthay et al. (2021) [2]). CONCLUSION: Balanced blood product transfusion reduces mortality for patients requiring ultramassive transfusion but when this is not possible utilization of adjuncts to blood products may temporize resuscitation until additional blood products can be obtained. Elsevier 2023-10-18 /pmc/articles/PMC10632100/ /pubmed/37955000 http://dx.doi.org/10.1016/j.tcr.2023.100955 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Jackson, Max
Berman, Spencer
Rueda, Mario
Borrego, Robert
Lottenberg, Lawrence
Azar, Faris
Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title_full Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title_fullStr Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title_full_unstemmed Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title_short Ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
title_sort ultramassive transfusion and adjunctive therapies in a case of blood bank depletion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632100/
https://www.ncbi.nlm.nih.gov/pubmed/37955000
http://dx.doi.org/10.1016/j.tcr.2023.100955
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