Cargando…

JAK-STAT signaling in inflammation and stress-related diseases: implications for therapeutic interventions

The Janus kinase-signal transducer and transcription activator pathway (JAK-STAT) serves as a cornerstone in cellular signaling, regulating physiological and pathological processes such as inflammation and stress. Dysregulation in this pathway can lead to severe immunodeficiencies and malignancies,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarapultsev, Alexey, Gusev, Evgenii, Komelkova, Maria, Utepova, Irina, Luo, Shanshan, Hu, Desheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632324/ https://www.ncbi.nlm.nih.gov/pubmed/37938494 http://dx.doi.org/10.1186/s43556-023-00151-1

Ejemplares similares

Atherosclerosis and Inflammation: Insights from the Theory of General Pathological Processes
por: Gusev, Evgenii, et al.
Publicado: (2023)

Problems of Pathogenesis and Pathogenetic Therapy of COVID-19 from the Perspective of the General Theory of Pathological Systems (General Pathological Processes)
por: Gusev, Evgenii, et al.
Publicado: (2021)

The Pathogenesis of End-Stage Renal Disease from the Standpoint of the Theory of General Pathological Processes of Inflammation
por: Gusev, Evgenii, et al.
Publicado: (2021)

SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19
por: Gusev, Evgenii, et al.
Publicado: (2022)

Big Five Traits as Predictors of a Healthy Lifestyle during the COVID-19 Pandemic: Results of a Russian Cross-Sectional Study
por: Zolotareva, Alena, et al.
Publicado: (2022)

Hexobarbital Sleep Test for Predicting the Susceptibility or Resistance to Experimental Posttraumatic Stress Disorder
por: Komelkova, Maria, et al.
Publicado: (2020)

Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications
por: Park, Hyunjung, et al.
Publicado: (2023)

Shock-Associated Systemic Inflammation in Amniotic Fluid Embolism, Complicated by Clinical Death
por: Brazhnikov, Anatoly, et al.
Publicado: (2023)

The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma
por: Ou, Alexander, et al.
Publicado: (2021)

The JAK-STAT pathway in hypertrophic stress signaling and genomic stress response
por: Wagner, Michael A., et al.
Publicado: (2012)

JAK/STAT pathway: Extracellular signals, diseases, immunity, and therapeutic regimens
por: Hu, Qian, et al.
Publicado: (2023)

Novelty, Stress, and Biological Roots in Human Market Behavior
por: Sarapultsev, Alexey, et al.
Publicado: (2014)

Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy
por: Zhang, Zili, et al.
Publicado: (2022)

JAK-STAT Signalling Pathway in Cancer
por: Brooks, Andrew J., et al.
Publicado: (2020)

JAK/STAT signaling in hepatocellular carcinoma
por: Hin Tang, Justin Jit, et al.
Publicado: (2020)

Editorial: Influence of the immune system on bone metabolism
por: Sarapultsev, Alexey, et al.
Publicado: (2023)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

JAK/STAT as a Potential Therapeutic Target for Osteolytic Diseases
por: Godoi, Mariely A., et al.
Publicado: (2023)

The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
por: Boyle, D L, et al.
Publicado: (2015)

C9ORF72 suppresses JAK-STAT mediated inflammation
por: Pang, Weilun, et al.
Publicado: (2023)

A review of JAK–STAT signalling in the pathogenesis of spondyloarthritis and the role of JAK inhibition
por: McInnes, Iain B, et al.
Publicado: (2021)

JAK/STAT signaling and human in vitro myogenesis
por: Trenerry, Marissa K, et al.
Publicado: (2011)

JAK-STAT signaling and myocardial glucose metabolism
por: Frias, Miguel A, et al.
Publicado: (2013)

The role of JAK-STAT signaling within the CNS
por: Nicolas, Celine S., et al.
Publicado: (2013)

JAK/STAT signaling in diabetic kidney disease
por: Liu, Yingjun, et al.
Publicado: (2023)

Therapeutic siRNAs Targeting the JAK/STAT Signalling Pathway in Inflammatory Bowel Diseases
por: Clément, Flora, et al.
Publicado: (2021)

A JAK/STAT invasion
por: Wells, William A.
Publicado: (2002)

JAK-STAT and bone metabolism
por: Li, Jiliang
Publicado: (2013)

The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

The JAK-STAT pathway at 20
por: Darnell, Jr., James E.
Publicado: (2012)

JAK-STAT in lymphoproliferative disorders
por: Rabadan, Raul, et al.
Publicado: (2015)

Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
por: Liu, Chang, et al.
Publicado: (2019)

Dihydroartemisinin attenuates pulmonary inflammation and fibrosis in rats by suppressing JAK2/STAT3 signaling
por: You, Xiaolan, et al.
Publicado: (2022)

Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway
por: Grusanovic, Srdjan, et al.
Publicado: (2022)

Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives
por: La Manna, Sara, et al.
Publicado: (2022)

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication
por: Loh, Chin-Yap, et al.
Publicado: (2019)

Delamanid suppresses CXCL10 expression via regulation of JAK/STAT1 signaling and correlates with reduced inflammation in tuberculosis patients
por: Qiao, Min, et al.
Publicado: (2022)

A centric view of JAK/STAT5 in intestinal homeostasis, infection, and inflammation
por: Surbek, Marta, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ouuq2bi417ds3adqf7idtnclov