Cargando…

The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration

As the primary site of T-cell development, the thymus dictates immune competency of the host. The rates of thymus function are not constant, and thymus regeneration is essential to restore new T-cell production following tissue damage from environmental factors and therapeutic interventions. Here, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cosway, Emilie J., James, Kieran D., White, Andrea J., Parnell, Sonia M., Bacon, Andrea, McKenzie, Andrew N. J., Jenkinson, W. E., Anderson, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632327/ https://www.ncbi.nlm.nih.gov/pubmed/37938566 http://dx.doi.org/10.1038/s41467-023-43072-x

Ejemplares similares

Failures in thymus medulla regeneration during immune recovery cause tolerance loss and prime recipients for auto-GVHD
por: Alawam, Abdullah S., et al.
Publicado: (2021)

Eosinophils Are An Essential Element Of A Type 2 Immune Axis That Controls Thymus Regeneration
por: Cosway, Emilie J., et al.
Publicado: (2022)

Redefining thymus medulla specialization for central tolerance
por: Cosway, Emilie J., et al.
Publicado: (2017)

Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus
por: Lucas, Beth, et al.
Publicado: (2016)

The thymus medulla and its control of αβT cell development
por: Cosway, Emilie J., et al.
Publicado: (2020)

Embryonic keratin19(+) progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla
por: Lucas, Beth, et al.
Publicado: (2023)

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7(+) Progenitors to the Thymus
por: Cosway, Emilie J., et al.
Publicado: (2018)

Alarmin IL-33 orchestrates antitumoral T cell responses to enhance sensitivity to 5-fluorouracil in colorectal cancer
por: Song, Mengjia, et al.
Publicado: (2023)

The Alarmin IL-33 Promotes Regulatory T Cell Function in the Intestine
por: Schiering, Chris, et al.
Publicado: (2014)

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk
por: White, Andrea J., et al.
Publicado: (2023)

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
por: Cohen, E. Suzanne, et al.
Publicado: (2015)

A type 2 cytokine axis for thymus emigration
por: White, Andrea J., et al.
Publicado: (2017)

The thymus and rheumatology: should we care?
por: Cosway, Emilie, et al.
Publicado: (2016)

Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2014)

Control of the thymic medulla and its influence on αβT‐cell development
por: Lucas, Beth, et al.
Publicado: (2016)

Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration
por: James, Kieran D., et al.
Publicado: (2018)

Alarmins in Osteoporosis, RAGE, IL-1, and IL-33 Pathways: A Literature Review
por: De Martinis, Massimo, et al.
Publicado: (2020)

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells
por: Lucas, Beth, et al.
Publicado: (2020)

The Role of Alarmins in Osteoarthritis Pathogenesis: HMGB1, S100B and IL-33
por: Palumbo, Antonino, et al.
Publicado: (2023)

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins
por: Bertheloot, Damien, et al.
Publicado: (2017)

Aire controls the recirculation of murine Foxp3(+) regulatory T‐cells back to the thymus
por: Cowan, Jennifer E., et al.
Publicado: (2018)

Alarmins HMGB1, IL-33, S100A7, and S100A12 in Psoriasis Vulgaris
por: Borsky, Pavel, et al.
Publicado: (2020)

Alarmin’ Immunologists: IL-33 as a Putative Target for Modulating T Cell-Dependent Responses
por: Gajardo Carrasco, Tania, et al.
Publicado: (2015)

The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33
por: Ferhat, Maroua Haroun, et al.
Publicado: (2018)

IL-33 and its increased serum levels as an alarmin for imminent pulmonary complications in polytraumatized patients
por: Halát, Gabriel, et al.
Publicado: (2019)

IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease
por: Perez, Federico, et al.
Publicado: (2020)

Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
por: Gundersen, Mona Dixon, et al.
Publicado: (2022)

Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis
por: Wong, Chun-Kwok, et al.
Publicado: (2012)

IL33 Is a Stomach Alarmin That Initiates a Skewed Th2 Response to Injury and Infection
por: Buzzelli, Jon N., et al.
Publicado: (2015)

Sound the Alarmin: Interleukin-33 Commandeers the Gastric Immune Response
por: Noto, Jennifer M., et al.
Publicado: (2015)

IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
por: Hardman, Clare S, et al.
Publicado: (2013)

IL-33, an Alarmin of the IL-1 Family Involved in Allergic and Non Allergic Inflammation: Focus on the Mechanisms of Regulation of Its Activity
por: Cayrol, Corinne
Publicado: (2021)

The Alarmin Concept Applied to Human Renal Transplantation: Evidence for a Differential Implication of HMGB1 and IL-33
por: Thierry, Antoine, et al.
Publicado: (2014)

Non-Epithelial Stromal Cells in Thymus Development and Function
por: James, Kieran D., et al.
Publicado: (2021)

Emerging roles for IL-25 and IL-33 in colorectal cancer tumorigenesis
por: Jou, Eric, et al.
Publicado: (2022)

An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
por: White, Andrea J., et al.
Publicado: (2014)

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?
por: Moussion, Christine, et al.
Publicado: (2008)

Sounding the alarmins—The role of alarmin cytokines in asthma
por: Gauvreau, Gail M., et al.
Publicado: (2022)

Differential expression of alarmins—S100A9, IL-33, HMGB1 and HIF-1α in supraspinatus tendinopathy before and after treatment
por: Mosca, Michael J, et al.
Publicado: (2017)

T‐cell egress from the thymus: Should I stay or should I go?
por: James, Kieran D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_98r0g4qr066gjm1m2f4bapbhem