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SIGNET: transcriptome-wide causal inference for gene regulatory networks

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Gene regulation plays an important role in understanding the mechanisms of human biology and diseases. However, inferring causal relationships between all genes is challenging due to the large number of genes in the transcriptome. Here, we present SIGNET (Statistical Inference on Gene Regulatory Net...

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Detalles Bibliográficos
Autores principales:	Jiang, Zhongli, Chen, Chen, Xu, Zhenyu, Wang, Xiaojian, Zhang, Min, Zhang, Dabao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632394/ https://www.ncbi.nlm.nih.gov/pubmed/37938594 http://dx.doi.org/10.1038/s41598-023-46295-6

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