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Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering
Allogeneic Vγ9Vδ2 (Vδ2) T cells have emerged as attractive candidates for developing cancer therapy due to their established safety in allogeneic contexts and inherent tumor-fighting capabilities. Nonetheless, the limited clinical success of Vδ2 T cell-based treatments may be attributed to donor var...
Autores principales: | Lee, Derek, Dunn, Zachary Spencer, Guo, Wenbin, Rosenthal, Carl J., Penn, Natalie E., Yu, Yanqi, Zhou, Kuangyi, Li, Zhe, Ma, Feiyang, Li, Miao, Song, Tsun-Ching, Cen, Xinjian, Li, Yan-Ruide, Zhou, Jin J., Pellegrini, Matteo, Wang, Pin, Yang, Lili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632431/ https://www.ncbi.nlm.nih.gov/pubmed/37938576 http://dx.doi.org/10.1038/s41467-023-42619-2 |
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