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Macular vessel density in central retinal artery occlusion with retinal arterial cannulation

To characterize and compare macular vessel density in central retinal artery occlusion (CRAO) eyes with retinal arterial cannulation and CRAO eyes with standard treatment. This study was Cross-sectional, observational study. Twenty-two eyes with nonarteric CRAO which underwent retinal arterial cannu...

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Autores principales: Soga, Naoki, Tanaka, Shin, Inoue, Maiko, Inoue, Tatsuya, Hayashi, Atsushi, de Juan, Eugene, Kadonosono, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632437/
https://www.ncbi.nlm.nih.gov/pubmed/37938610
http://dx.doi.org/10.1038/s41598-023-46267-w
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author Soga, Naoki
Tanaka, Shin
Inoue, Maiko
Inoue, Tatsuya
Hayashi, Atsushi
de Juan, Eugene
Kadonosono, Kazuaki
author_facet Soga, Naoki
Tanaka, Shin
Inoue, Maiko
Inoue, Tatsuya
Hayashi, Atsushi
de Juan, Eugene
Kadonosono, Kazuaki
author_sort Soga, Naoki
collection PubMed
description To characterize and compare macular vessel density in central retinal artery occlusion (CRAO) eyes with retinal arterial cannulation and CRAO eyes with standard treatment. This study was Cross-sectional, observational study. Twenty-two eyes with nonarteric CRAO which underwent retinal arterial cannulation and 19 eyes with nonarteric CRAO with standard treatment were included. Optical coherent tomography angiography (OCTA)-based macular vessel density and visual acuity were examined. The dynamic ranged-based normalized rates of vessel density was compared within each group at the first visit to the clinic and 7 days after the onset. Macular vessel density in cannulation group was significantly better at 7 days after the onset than that at the first visit (3.73 ± 3.02 mm(−1) vs. 7.89 ± 1.02 mm(−1), P = 0.0001), while there wasn’t significant improvement of macular vessel density in standard treatment group at 7 days after the onset (2.13 ± 1.62 mm(−1) vs. 2.89 ± 0.22 mm(−1), P = 0.067). At one month after the onset, mean LogMAR visual acuity in CRAO eyes with cannulation significantly improved compared with that at the first visit after the onset (1.678 vs. 0.979, P = 0.00012). Macular vessel density loss in CRAO eyes was improved by retinal arterial cannulation. Early intervention of retinal arterial cannulation is useful for minimizing visual impairment in CRAO eyes.
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spelling pubmed-106324372023-11-10 Macular vessel density in central retinal artery occlusion with retinal arterial cannulation Soga, Naoki Tanaka, Shin Inoue, Maiko Inoue, Tatsuya Hayashi, Atsushi de Juan, Eugene Kadonosono, Kazuaki Sci Rep Article To characterize and compare macular vessel density in central retinal artery occlusion (CRAO) eyes with retinal arterial cannulation and CRAO eyes with standard treatment. This study was Cross-sectional, observational study. Twenty-two eyes with nonarteric CRAO which underwent retinal arterial cannulation and 19 eyes with nonarteric CRAO with standard treatment were included. Optical coherent tomography angiography (OCTA)-based macular vessel density and visual acuity were examined. The dynamic ranged-based normalized rates of vessel density was compared within each group at the first visit to the clinic and 7 days after the onset. Macular vessel density in cannulation group was significantly better at 7 days after the onset than that at the first visit (3.73 ± 3.02 mm(−1) vs. 7.89 ± 1.02 mm(−1), P = 0.0001), while there wasn’t significant improvement of macular vessel density in standard treatment group at 7 days after the onset (2.13 ± 1.62 mm(−1) vs. 2.89 ± 0.22 mm(−1), P = 0.067). At one month after the onset, mean LogMAR visual acuity in CRAO eyes with cannulation significantly improved compared with that at the first visit after the onset (1.678 vs. 0.979, P = 0.00012). Macular vessel density loss in CRAO eyes was improved by retinal arterial cannulation. Early intervention of retinal arterial cannulation is useful for minimizing visual impairment in CRAO eyes. Nature Publishing Group UK 2023-11-08 /pmc/articles/PMC10632437/ /pubmed/37938610 http://dx.doi.org/10.1038/s41598-023-46267-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Soga, Naoki
Tanaka, Shin
Inoue, Maiko
Inoue, Tatsuya
Hayashi, Atsushi
de Juan, Eugene
Kadonosono, Kazuaki
Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title_full Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title_fullStr Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title_full_unstemmed Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title_short Macular vessel density in central retinal artery occlusion with retinal arterial cannulation
title_sort macular vessel density in central retinal artery occlusion with retinal arterial cannulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632437/
https://www.ncbi.nlm.nih.gov/pubmed/37938610
http://dx.doi.org/10.1038/s41598-023-46267-w
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