Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms

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Magnesium ions (Mg(2+)) play an essential role in cellular physiology. In mitochondria, protein and ATP synthesis and various metabolic pathways are directly regulated by Mg(2+). MRS2, a magnesium channel located in the inner mitochondrial membrane, mediates the influx of Mg(2+) into the mitochondri...

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Detalles Bibliográficos
Autores principales: Lai, Louis Tung Faat, Balaraman, Jayashree, Zhou, Fei, Matthies, Doreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632456/
https://www.ncbi.nlm.nih.gov/pubmed/37938562
http://dx.doi.org/10.1038/s41467-023-42599-3

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