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The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction

Germline mutations of E-cadherin cause Hereditary Diffuse Gastric Cancer (HDGC), a highly invasive cancer syndrome characterised by the occurrence of diffuse-type gastric carcinoma and lobular breast cancer. In this disease, E-cadherin-defective cells are detected invading the adjacent stroma since...

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Detalles Bibliográficos
Autores principales:	Melo, Soraia, Guerrero, Pilar, Moreira Soares, Maurício, Bordin, José Rafael, Carneiro, Fátima, Carneiro, Patrícia, Dias, Maria Beatriz, Carvalho, João, Figueiredo, Joana, Seruca, Raquel, Travasso, Rui D. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632478/ https://www.ncbi.nlm.nih.gov/pubmed/37938268 http://dx.doi.org/10.1038/s42003-023-05482-x

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