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Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients

Efficacy of cancer vaccines remains low and mechanistic understanding of antigen presenting cell function in cancer may improve vaccine design and outcomes. Here, we analyze the transcriptomic and immune-metabolic profiles of Dendritic Cells (DCs) from 35 subjects enrolled in a trial of DC vaccines...

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Detalles Bibliográficos
Autores principales: Adamik, Juraj, Munson, Paul V., Maurer, Deena M., Hartmann, Felix J., Bendall, Sean C., Argüello, Rafael J., Butterfield, Lisa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632482/
https://www.ncbi.nlm.nih.gov/pubmed/37938561
http://dx.doi.org/10.1038/s41467-023-42881-4