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Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short

BACKGROUND/OBJECTIVES: Nutrition and obesity researchers often dichotomize or discretize continuous independent variables to conduct an analysis of variance to examine group differences. We describe consequences associated with dichotomizing and discretizing continuous variables using two cross-sect...

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Autores principales: Morera, Osvaldo F., Dane’el, Mosi I., Smith, Brandt A., Redelfs, Alisha H., Ruiz, Sarah L., Preacher, Kristopher J., Whigham, Leah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632499/
https://www.ncbi.nlm.nih.gov/pubmed/37938224
http://dx.doi.org/10.1038/s41387-023-00248-0
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author Morera, Osvaldo F.
Dane’el, Mosi I.
Smith, Brandt A.
Redelfs, Alisha H.
Ruiz, Sarah L.
Preacher, Kristopher J.
Whigham, Leah D.
author_facet Morera, Osvaldo F.
Dane’el, Mosi I.
Smith, Brandt A.
Redelfs, Alisha H.
Ruiz, Sarah L.
Preacher, Kristopher J.
Whigham, Leah D.
author_sort Morera, Osvaldo F.
collection PubMed
description BACKGROUND/OBJECTIVES: Nutrition and obesity researchers often dichotomize or discretize continuous independent variables to conduct an analysis of variance to examine group differences. We describe consequences associated with dichotomizing and discretizing continuous variables using two cross-sectional studies related to nutrition. SUBJECTS/METHODS: Study 1 investigated the effects of health literacy and nutrition knowledge on nutrition label accuracy (n = 612). Study 2 investigated the effects of cognitive restraint and BMI on fruit and vegetable (F/V) intake (n = 586). We compare analytic approaches where continuous independent variables were either discretized/dichotomized or analyzed as continuous variables. RESULTS: In Study 1, dichotomization of health literacy and nutrition knowledge for 2 × 2 ANOVA revealed health literacy had an effect on nutrition label accuracy. Nutrition knowledge has an effect on nutrition label accuracy, but the health literacy by nutrition knowledge interaction was not significant. When analyzed using regression, the nutrition knowledge effect was significant. The simple effect of health literacy was also significant when health literacy equals zero. Finally, the quadratic effect of health literacy was negative and significant. In Study 2, dichotomization and discretization of cognitive restraint and BMI were used for three ANOVAs, which discretized BMI in three ways. For all ANOVAs, the BMI main effect for predicting fruit and vegetable intake was significant, the interaction between BMI and cognitive restraint was non-significant, and cognitive restraint was only significant when both variables were dichotomized. When analyzed using regression, the continuous mean-centered variables, and their interaction each significantly predicted F/V intake. CONCLUSIONS: Dichotomizing continuous independent variables resulted in distortions of effect sizes across studies, an inability to assess the quadratic effect of health literacy, and an inability to detect the moderating effect of BMI. We discourage researchers from dichotomizing and discretizing continuous independent variables and instead use multiple regression to examine relationships between continuous independent and dependent variables.
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spelling pubmed-106324992023-11-10 Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short Morera, Osvaldo F. Dane’el, Mosi I. Smith, Brandt A. Redelfs, Alisha H. Ruiz, Sarah L. Preacher, Kristopher J. Whigham, Leah D. Nutr Diabetes Article BACKGROUND/OBJECTIVES: Nutrition and obesity researchers often dichotomize or discretize continuous independent variables to conduct an analysis of variance to examine group differences. We describe consequences associated with dichotomizing and discretizing continuous variables using two cross-sectional studies related to nutrition. SUBJECTS/METHODS: Study 1 investigated the effects of health literacy and nutrition knowledge on nutrition label accuracy (n = 612). Study 2 investigated the effects of cognitive restraint and BMI on fruit and vegetable (F/V) intake (n = 586). We compare analytic approaches where continuous independent variables were either discretized/dichotomized or analyzed as continuous variables. RESULTS: In Study 1, dichotomization of health literacy and nutrition knowledge for 2 × 2 ANOVA revealed health literacy had an effect on nutrition label accuracy. Nutrition knowledge has an effect on nutrition label accuracy, but the health literacy by nutrition knowledge interaction was not significant. When analyzed using regression, the nutrition knowledge effect was significant. The simple effect of health literacy was also significant when health literacy equals zero. Finally, the quadratic effect of health literacy was negative and significant. In Study 2, dichotomization and discretization of cognitive restraint and BMI were used for three ANOVAs, which discretized BMI in three ways. For all ANOVAs, the BMI main effect for predicting fruit and vegetable intake was significant, the interaction between BMI and cognitive restraint was non-significant, and cognitive restraint was only significant when both variables were dichotomized. When analyzed using regression, the continuous mean-centered variables, and their interaction each significantly predicted F/V intake. CONCLUSIONS: Dichotomizing continuous independent variables resulted in distortions of effect sizes across studies, an inability to assess the quadratic effect of health literacy, and an inability to detect the moderating effect of BMI. We discourage researchers from dichotomizing and discretizing continuous independent variables and instead use multiple regression to examine relationships between continuous independent and dependent variables. Nature Publishing Group UK 2023-11-08 /pmc/articles/PMC10632499/ /pubmed/37938224 http://dx.doi.org/10.1038/s41387-023-00248-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Morera, Osvaldo F.
Dane’el, Mosi I.
Smith, Brandt A.
Redelfs, Alisha H.
Ruiz, Sarah L.
Preacher, Kristopher J.
Whigham, Leah D.
Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title_full Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title_fullStr Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title_full_unstemmed Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title_short Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
title_sort discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632499/
https://www.ncbi.nlm.nih.gov/pubmed/37938224
http://dx.doi.org/10.1038/s41387-023-00248-0
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