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SCF(βTrCP)-mediated degradation of SHARP1 in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a subtype of breast cancer associated with metastasis, high recurrence rate, and poor survival. The basic helix-loop-helix transcription factor SHARP1 (Split and Hairy-related Protein 1) has been identified as a suppressor of the metastatic behavior of TNBC. S...

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Detalles Bibliográficos
Autores principales:	Enriqué Steinberg, Juliana Haydeé, Rossi, Fabiana Alejandra, Magliozzi, Roberto, Yuniati, Laurensia, Santucci, Matteo, Rossi, Mario, Guardavaccaro, Daniele, Lauriola, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632515/ https://www.ncbi.nlm.nih.gov/pubmed/37938564 http://dx.doi.org/10.1038/s41419-023-06253-6

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