Cargando…

SCF(βTrCP)-mediated degradation of SHARP1 in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a subtype of breast cancer associated with metastasis, high recurrence rate, and poor survival. The basic helix-loop-helix transcription factor SHARP1 (Split and Hairy-related Protein 1) has been identified as a suppressor of the metastatic behavior of TNBC. S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Enriqué Steinberg, Juliana Haydeé, Rossi, Fabiana Alejandra, Magliozzi, Roberto, Yuniati, Laurensia, Santucci, Matteo, Rossi, Mario, Guardavaccaro, Daniele, Lauriola, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632515/ https://www.ncbi.nlm.nih.gov/pubmed/37938564 http://dx.doi.org/10.1038/s41419-023-06253-6

Ejemplares similares

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase
por: Magliozzi, Roberto, et al.
Publicado: (2015)

USP7 counteracts SCF(βTrCP)- but not APC(Cdh1)-mediated proteolysis of Claspin
por: Faustrup, Helene, et al.
Publicado: (2009)

SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
por: Ma, Ying, et al.
Publicado: (2018)

Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction
por: Jaffry, Uzma, et al.
Publicado: (2023)

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
por: Mavrommati, Ioanna, et al.
Publicado: (2018)

SCF(β-TrCP)-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II
por: Shu, Jianfeng, et al.
Publicado: (2020)

β-TrCP1 facilitates cell cycle checkpoint activation, DNA repair, and cell survival through ablation of β-TrCP2 in response to genotoxic stress
por: Islam, Sehbanul, et al.
Publicado: (2021)

E3 Ligase SCF(βTrCP)-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells
por: Liu, Qiang, et al.
Publicado: (2016)

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
por: Bufalieri, Francesca, et al.
Publicado: (2019)

NORE1A Regulates MDM2 Via β-TrCP
por: Schmidt, M. Lee, et al.
Publicado: (2016)

Structural basis of βTrCP1-associated GLI3 processing
por: Shafique, Shagufta, et al.
Publicado: (2019)

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression
por: Seki, Akiko, et al.
Publicado: (2008)

β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
por: Cheng, Yun, et al.
Publicado: (2016)

Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis
por: Krishnamurthy, Pranathi Meda, et al.
Publicado: (2017)

The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
por: Cui, Danrui, et al.
Publicado: (2019)

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor
por: Paul, Debasish, et al.
Publicado: (2022)

SCF(β-TRCP) regulates osteoclastogenesis via promoting CYLD ubiquitination
por: Wu, Xiaomian, et al.
Publicado: (2014)

Aspirin attenuates YAP and β-catenin expression by promoting β-TrCP to overcome docetaxel and vinorelbine resistance in triple-negative breast cancer
por: Ma, Ji, et al.
Publicado: (2020)

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP
por: Tatarskiy, Victor V., et al.
Publicado: (2017)

β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
por: Wang, Dongping, et al.
Publicado: (2019)

Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β(MYPT1) phosphatase complex and the SCF(βTrCP) E3 ubiquitin ligase
por: Banerjee, Sourav, et al.
Publicado: (2014)

Calyxin Y sensitizes cisplatin-sensitive and resistant hepatocellular carcinoma cells to cisplatin through apoptotic and autophagic cell death via SCF βTrCP-mediated eEF2K degradation
por: Zhang, Chao, et al.
Publicado: (2017)

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor
por: Gluschnaider, Udi, et al.
Publicado: (2010)

Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase
por: Jiang, Hui, et al.
Publicado: (2011)

PLK1 and β-TrCP-Dependent Ubiquitination and Degradation of Rap1GAP Controls Cell Proliferation
por: Wang, Dejie, et al.
Publicado: (2014)

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy
por: Herrero-Ruiz, Joaquín, et al.
Publicado: (2014)

Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
por: Benary, Uwe, et al.
Publicado: (2019)

F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2
por: Lee, Cheol-Jung, et al.
Publicado: (2021)

TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells
por: Yi, Yong Weon, et al.
Publicado: (2015)

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release
por: Tervo, Hanna-Mari, et al.
Publicado: (2011)

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
por: Chan, Eunice H. Y., et al.
Publicado: (2008)

Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
por: Maluquer de Motes, Carlos, et al.
Publicado: (2017)

Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis
por: Xiong, Xiufang, et al.
Publicado: (2018)

MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells
por: Xu, Huanji, et al.
Publicado: (2019)

CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway
por: Bu, Xin, et al.
Publicado: (2021)

Correction: TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking
por: Mitchell, Richard S., et al.
Publicado: (2009)

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1
por: Blees, Johanna S., et al.
Publicado: (2012)

GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression
por: Zhu, Yuekun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_39plvgfv3sqenp1c6ains2f4n8