Dimensionality reduction methods for extracting functional networks from large‐scale CRISPR screens

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CRISPR‐Cas9 screens facilitate the discovery of gene functional relationships and phenotype‐specific dependencies. The Cancer Dependency Map (DepMap) is the largest compendium of whole‐genome CRISPR screens aimed at identifying cancer‐specific genetic dependencies across human cell lines. A mitochon...

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Detalles Bibliográficos
Autores principales: Hassan, Arshia Zernab, Ward, Henry N, Rahman, Mahfuzur, Billmann, Maximilian, Lee, Yoonkyu, Myers, Chad L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632734/
https://www.ncbi.nlm.nih.gov/pubmed/37750448
http://dx.doi.org/10.15252/msb.202311657

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