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Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Despite the successful application of immune checkpoint blockade in a range of human cancers, immunotherapy in PDAC remains unsuccessful. PDAC is characterized by a desmoplastic, hypoxic and highly immunosuppressive...

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Detalles Bibliográficos
Autores principales:	Boelaars, Kelly, Goossens-Kruijssen, Laura, Wang, Di, de Winde, Charlotte M, Rodriguez, Ernesto, Lindijer, Dimitri, Springer, Babet, van der Haar Àvila, Irene, de Haas, Aram, Wehry, Laetitia, Boon, Louis, Mebius, Reina E, van Montfoort, Nadine, Wuhrer, Manfred, den Haan, Joke M M, van Vliet, Sandra J, van Kooyk, Yvette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632901/ https://www.ncbi.nlm.nih.gov/pubmed/37940346 http://dx.doi.org/10.1136/jitc-2023-007805

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