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A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer

BACKGROUND: Immunotherapy targeting the PD-1/PD-L1 pathway is a standard of care in a number of metastatic malignancies, but less than a fifth of patients are expected to respond to ICIs (Immune Checkpoint Inhibitors). In a clinical trial, combining the anti-TIGIT (T cell immunoreceptor with Ig and...

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Detalles Bibliográficos
Autores principales:	Roussot, Nicolas, Fumet, Jean-David, Limagne, Emeric, Thibaudin, Marion, Hervieu, Alice, Hennequin, Audrey, Zanetta, Sylvie, Dalens, Lorraine, Fourrier, Théo, Galland, Loick, Jacob, Pierre, Bertaut, Aurélie, Rederstorff, Emilie, Chevalier, Cédric, Ghirardi, Sarah, Gilbert, Elodie, Khoukaz, Azzat, Martin, Etienne, Nicolet, Constance, Quivrin, Magali, Thibouw, David, Vulquin, Noémie, Truc, Gilles, Rouffiac, Magali, Ghiringhelli, Francois, Mirjolet, Céline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633948/ https://www.ncbi.nlm.nih.gov/pubmed/37946136 http://dx.doi.org/10.1186/s12885-023-11534-6

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