Cargando…

Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition

INTRODUCTION: The typical outcome of mammalian wound healing is scarring, a fibrotic process mediated by myofibroblast aggregation. Perfect healing in a clinical setting is relatively unexplored. Surprisingly, our previous studies have shown that the large wound (10 cm diameter or more) of the pedic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Guokun, Wang, Dongxu, Ren, Jing, Li, Jiping, Guo, Qianqian, Shi, Liyan, Li, Chunyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633995/ https://www.ncbi.nlm.nih.gov/pubmed/37940994 http://dx.doi.org/10.1186/s13036-023-00386-0

Ejemplares similares

Antler stem cell-conditioned medium stimulates regenerative wound healing in rats
por: Rong, Xiaoli, et al.
Publicado: (2019)

Velvet Antler Peptides Reduce Scarring via Inhibiting the TGF-β Signaling Pathway During Wound Healing
por: Zhang, Guokun, et al.
Publicado: (2022)

Transplanted Antler Stem Cells Stimulated Regenerative Healing of Radiation-induced Cutaneous Wounds in Rats
por: Rong, Xiaoli, et al.
Publicado: (2020)

Antler stem cell exosomes alleviate pulmonary fibrosis via inhibiting recruitment of monocyte macrophage, rather than polarization of M2 macrophages in mice
por: Zhang, Guokun, et al.
Publicado: (2023)

Fibroblasts and myofibroblasts in wound healing
por: Darby, Ian A, et al.
Publicado: (2014)

Tracing the geographic origin of velvet antlers in China via stable isotope analyses
por: Zhao, Haiping, et al.
Publicado: (2022)

Antler stem cells and their potential in wound healing and bone regeneration
por: Zhang, Wei, et al.
Publicado: (2021)

Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
por: Yao, Longbiao, et al.
Publicado: (2022)

Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche
por: Zhang, Guo-Kun, et al.
Publicado: (2023)

IGF1R and LOX Modules Are Related to Antler Growth Rate Revealed by Integrated Analyses of Genomics and Transcriptomics
por: Hu, Pengfei, et al.
Publicado: (2022)

Identification and Characterization of Alternative Splicing Variants and Positive Selection Genes Related to Distinct Growth Rates of Antlers Using Comparative Transcriptome Sequencing
por: Hu, Pengfei, et al.
Publicado: (2022)

Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis
por: Lei, Jinghui, et al.
Publicado: (2021)

Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor inhibition
por: Zhang, Yan, et al.
Publicado: (2021)

Fibroblasts: Heterogeneous Cells With Potential in Regenerative Therapy for Scarless Wound Healing
por: Zou, Ming-Li, et al.
Publicado: (2021)

Fibroblasts, myofibroblasts, and wound contraction
Publicado: (1994)

Effects of p21 Gene Down-Regulation through RNAi on Antler Stem Cells In Vitro
por: Guo, Qianqian, et al.
Publicado: (2015)

Proteomes and Signalling Pathways of Antler Stem Cells
por: Li, Chunyi, et al.
Publicado: (2012)

Extracellular vesicles derived from umbilical cord mesenchymal stromal cells alleviate pulmonary fibrosis by means of transforming growth factor-β signaling inhibition
por: Shi, Liyan, et al.
Publicado: (2021)

Engineered stem cell exosomes for oral and maxillofacial wound healing
por: Hao, Ming, et al.
Publicado: (2022)

Placental stem cells-derived exosomes stimulate cutaneous wound regeneration via engrailed-1 inhibition
por: Zhang, Yan, et al.
Publicado: (2022)

Deer antler stem cells are a novel type of cells that sustain full regeneration of a mammalian organ—deer antler
por: Wang, Datao, et al.
Publicado: (2019)

Conditioned media of deer antler stem cells accelerate regeneration of alveolar bone defects in rats
por: Guo, Qianqian, et al.
Publicado: (2023)

Deer antler renewal gives insights into mammalian epimorphic regeneration
por: Li, Chunyi
Publicado: (2023)

Physicochemically Tuned Myofibroblasts for Wound Healing Strategy
por: Ko, Ung Hyun, et al.
Publicado: (2019)

Electrical Stimulation Promotes Wound Healing by Enhancing Dermal Fibroblast Activity and Promoting Myofibroblast Transdifferentiation
por: Rouabhia, Mahmoud, et al.
Publicado: (2013)

Fibroblast-to-myofibroblast transition in bronchial asthma
por: Michalik, Marta, et al.
Publicado: (2018)

Stem Cells and Engineered Scaffolds for Regenerative Wound Healing
por: Dash, Biraja C., et al.
Publicado: (2018)

Novel prospects for scarless wound healing: The roles of myofibroblasts and adipocytes
por: Teng, Ying‐Ying, et al.
Publicado: (2022)

Morphogenetic Mechanisms in the Cyclic Regeneration of Hair Follicles and Deer Antlers from Stem Cells
por: Li, Chunyi, et al.
Publicado: (2013)

The myofibroblast in wound healing and fibrosis: answered and unanswered questions
por: Bochaton-Piallat, Marie-Luce, et al.
Publicado: (2016)

Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing
por: Duan, Mengna, et al.
Publicado: (2020)

Abstract 5: Inhibition of Mechanotransduction Yields Regenerative Wound Healing by Engrailed1-negative Fibroblasts
por: Mascharak, Shamik, et al.
Publicado: (2019)

iTRAQ-Based Quantitative Proteomic Analysis of the Potentiated and Dormant Antler Stem Cells
por: Dong, Zhen, et al.
Publicado: (2016)

Corneal myofibroblasts inhibit regenerating nerves during wound healing
por: Jeon, Kye-Im, et al.
Publicado: (2018)

Wound Healing Myofibroblasts Proliferate Clonally and in a Mechanoresponsive Manner
por: Chinta, Malini, et al.
Publicado: (2020)

The periosteum: a simple tissue with many faces, with special reference to the antler-lineage periostea
por: Li, Chunyi, et al.
Publicado: (2021)

Aclidinium inhibits human lung fibroblast to myofibroblast transition
por: Milara, Javier, et al.
Publicado: (2011)

Fibroblast to myofibroblast transition is enhanced by increased cell density
por: Doolin, Mary T., et al.
Publicado: (2021)

Single-cell transcriptome reveals core cell populations and androgen-RXFP2 axis involved in deer antler full regeneration
por: Ba, Hengxing, et al.
Publicado: (2022)

Cross-Species Analysis Reveals Co-Expressed Genes Regulating Antler Development in Cervidae
por: Ba, Hengxing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4mfi0e8ohihttma2jeq958296i