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Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury

OBJECTIVE: To investigate the mechanism of action of Srg3 in acute lung injury caused by sepsis. METHODS: First, a sepsis-induced acute lung injury rat model was established using cecal ligation and puncture (CLP). RNA sequencing (RNA-seq) was used to screen for highly expressed genes in sepsis-indu...

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Detalles Bibliográficos
Autores principales: Ling, Xinyu, Wei, Shiyou, Ling, Dandan, Cao, Siqi, Chang, Rui, Wang, Qiuyun, Yuan, Zhize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634032/
https://www.ncbi.nlm.nih.gov/pubmed/37946128
http://dx.doi.org/10.1186/s11658-023-00495-0