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The immunomodulating activity of trimodulin (polyvalent IgM, IgA, IgG solution): a post hoc analysis of the phase II CIGMA trial
BACKGROUND: The phase II CIGMA trial performed in 160 patients with severe community-acquired pneumonia (sCAP) found treatment with trimodulin (human polyvalent immunoglobulin [Ig]: ~ 23% IgM, ~ 21% IgA, ~ 56% IgG) was associated with a lower mortality in those patients with elevated baseline serum...
Autores principales: | Singer, Mervyn, Torres, Antoni, Heinz, Corina C., Weißmüller, Sabrina, Staus, Alexander, Kistner, Steffen, Jakubczyk, Ksenia, Häder, Thomas, Langohr, Patrick, Wartenberg-Demand, Andrea, Schüttrumpf, Jörg, Vincent, Jean-Louis, Welte, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634136/ https://www.ncbi.nlm.nih.gov/pubmed/37946226 http://dx.doi.org/10.1186/s13054-023-04719-9 |
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