Cargando…
Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma
Radiation-induced cerebral necrosis, also known as radiation encephalopathy, is a debilitating condition that significantly impacts the quality of life for affected patients. Secondary central nervous system lymphoma (SCNSL) typically arises from highly aggressive mature B-cell lymphoma, but rarely...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634224/ https://www.ncbi.nlm.nih.gov/pubmed/37954919 http://dx.doi.org/10.3389/fradi.2023.1257565 |
_version_ | 1785132787407257600 |
---|---|
author | Chen, Boxiao Fan, Yili Wang, Luyao Zhang, Jiawei Xin, Dijia Qiu, Xi Jiang, Huawei Li, Baizhou Chen, Qin Wang, Chao Xiao, Xibin Huang, Liansheng Xu, Yang |
author_facet | Chen, Boxiao Fan, Yili Wang, Luyao Zhang, Jiawei Xin, Dijia Qiu, Xi Jiang, Huawei Li, Baizhou Chen, Qin Wang, Chao Xiao, Xibin Huang, Liansheng Xu, Yang |
author_sort | Chen, Boxiao |
collection | PubMed |
description | Radiation-induced cerebral necrosis, also known as radiation encephalopathy, is a debilitating condition that significantly impacts the quality of life for affected patients. Secondary central nervous system lymphoma (SCNSL) typically arises from highly aggressive mature B-cell lymphoma, but rarely from extranodal natural killer T-cell lymphoma (ENKTL). Treatment will be guided by differentiation between lymphoma progression from brain necrosis, and is particularly important for critically ill patients in an acute setting. However, differential diagnosis remains challenging because they share similar clinical manifestations and have no specific imaging features. We present the case of a 52-year-old man with ENKTL who suffered an emergency brain herniation secondary to massive radiation necrosis. The diagnosis established by brain biopsy ultimately led to appropriate treatment. The importance of the diagnostic biopsy is highlighted in this case for distinguishing between radiation necrosis and SCNSL. |
format | Online Article Text |
id | pubmed-10634224 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106342242023-11-10 Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma Chen, Boxiao Fan, Yili Wang, Luyao Zhang, Jiawei Xin, Dijia Qiu, Xi Jiang, Huawei Li, Baizhou Chen, Qin Wang, Chao Xiao, Xibin Huang, Liansheng Xu, Yang Front Radiol Radiology Radiation-induced cerebral necrosis, also known as radiation encephalopathy, is a debilitating condition that significantly impacts the quality of life for affected patients. Secondary central nervous system lymphoma (SCNSL) typically arises from highly aggressive mature B-cell lymphoma, but rarely from extranodal natural killer T-cell lymphoma (ENKTL). Treatment will be guided by differentiation between lymphoma progression from brain necrosis, and is particularly important for critically ill patients in an acute setting. However, differential diagnosis remains challenging because they share similar clinical manifestations and have no specific imaging features. We present the case of a 52-year-old man with ENKTL who suffered an emergency brain herniation secondary to massive radiation necrosis. The diagnosis established by brain biopsy ultimately led to appropriate treatment. The importance of the diagnostic biopsy is highlighted in this case for distinguishing between radiation necrosis and SCNSL. Frontiers Media S.A. 2023-10-25 /pmc/articles/PMC10634224/ /pubmed/37954919 http://dx.doi.org/10.3389/fradi.2023.1257565 Text en © 2023 Chen, Fan, Wang, Zhang, Xin, Qiu, Jiang, Li, Chen, Wang, Xiao, Huang and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Radiology Chen, Boxiao Fan, Yili Wang, Luyao Zhang, Jiawei Xin, Dijia Qiu, Xi Jiang, Huawei Li, Baizhou Chen, Qin Wang, Chao Xiao, Xibin Huang, Liansheng Xu, Yang Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title | Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title_full | Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title_fullStr | Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title_full_unstemmed | Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title_short | Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma |
title_sort | case report: radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/t-cell lymphoma |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634224/ https://www.ncbi.nlm.nih.gov/pubmed/37954919 http://dx.doi.org/10.3389/fradi.2023.1257565 |
work_keys_str_mv | AT chenboxiao casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT fanyili casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT wangluyao casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT zhangjiawei casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT xindijia casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT qiuxi casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT jianghuawei casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT libaizhou casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT chenqin casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT wangchao casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT xiaoxibin casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT huangliansheng casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma AT xuyang casereportradiationnecrosismimickingtumorprogressioninapatientwithextranodalnaturalkillertcelllymphoma |