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Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects

Gastrointestinal (GI) cancer is the leading cause of cancer-related deaths worldwide. Computed tomography (CT) is an important auxiliary tool for the diagnosis, evaluation, and prognosis prediction of gastrointestinal tumors. Spectral CT is another major CT revolution after spiral CT and multidetect...

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Autores principales: Hong, Yuqin, Zhong, Lijuan, Lv, Xue, Liu, Qiao, Fu, Langzhou, Zhou, Daiquan, Yu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634296/
https://www.ncbi.nlm.nih.gov/pubmed/37954980
http://dx.doi.org/10.3389/fmolb.2023.1284549
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author Hong, Yuqin
Zhong, Lijuan
Lv, Xue
Liu, Qiao
Fu, Langzhou
Zhou, Daiquan
Yu, Na
author_facet Hong, Yuqin
Zhong, Lijuan
Lv, Xue
Liu, Qiao
Fu, Langzhou
Zhou, Daiquan
Yu, Na
author_sort Hong, Yuqin
collection PubMed
description Gastrointestinal (GI) cancer is the leading cause of cancer-related deaths worldwide. Computed tomography (CT) is an important auxiliary tool for the diagnosis, evaluation, and prognosis prediction of gastrointestinal tumors. Spectral CT is another major CT revolution after spiral CT and multidetector CT. Compared to traditional CT which only provides single-parameter anatomical diagnostic mode imaging, spectral CT can achieve multi-parameter imaging and provide a wealth of image information to optimize disease diagnosis. In recent years, with the rapid development and application of spectral CT, more and more studies on the application of spectral CT in the characterization of GI tumors have been published. For this review, we obtained a substantial volume of literature, focusing on spectral CT imaging of gastrointestinal cancers, including esophageal, stomach, colorectal, liver, and pancreatic cancers. We found that spectral CT can not only accurately stage gastrointestinal tumors before operation but also distinguish benign and malignant GI tumors with improved image quality, and effectively evaluate the therapeutic response and prognosis of the lesions. In addition, this paper also discusses the limitations and prospects of using spectral CT in GI cancer diagnosis and treatment.
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spelling pubmed-106342962023-11-10 Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects Hong, Yuqin Zhong, Lijuan Lv, Xue Liu, Qiao Fu, Langzhou Zhou, Daiquan Yu, Na Front Mol Biosci Molecular Biosciences Gastrointestinal (GI) cancer is the leading cause of cancer-related deaths worldwide. Computed tomography (CT) is an important auxiliary tool for the diagnosis, evaluation, and prognosis prediction of gastrointestinal tumors. Spectral CT is another major CT revolution after spiral CT and multidetector CT. Compared to traditional CT which only provides single-parameter anatomical diagnostic mode imaging, spectral CT can achieve multi-parameter imaging and provide a wealth of image information to optimize disease diagnosis. In recent years, with the rapid development and application of spectral CT, more and more studies on the application of spectral CT in the characterization of GI tumors have been published. For this review, we obtained a substantial volume of literature, focusing on spectral CT imaging of gastrointestinal cancers, including esophageal, stomach, colorectal, liver, and pancreatic cancers. We found that spectral CT can not only accurately stage gastrointestinal tumors before operation but also distinguish benign and malignant GI tumors with improved image quality, and effectively evaluate the therapeutic response and prognosis of the lesions. In addition, this paper also discusses the limitations and prospects of using spectral CT in GI cancer diagnosis and treatment. Frontiers Media S.A. 2023-10-25 /pmc/articles/PMC10634296/ /pubmed/37954980 http://dx.doi.org/10.3389/fmolb.2023.1284549 Text en Copyright © 2023 Hong, Zhong, Lv, Liu, Fu, Zhou and Yu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Hong, Yuqin
Zhong, Lijuan
Lv, Xue
Liu, Qiao
Fu, Langzhou
Zhou, Daiquan
Yu, Na
Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title_full Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title_fullStr Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title_full_unstemmed Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title_short Application of spectral CT in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
title_sort application of spectral ct in diagnosis, classification and prognostic monitoring of gastrointestinal cancers: progress, limitations and prospects
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634296/
https://www.ncbi.nlm.nih.gov/pubmed/37954980
http://dx.doi.org/10.3389/fmolb.2023.1284549
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