Cargando…
Mutational hotspots lead to robust but suboptimal adaptive outcomes in certain environments
The observed mutational spectrum of adaptive outcomes can be constrained by many factors. For example, mutational biases can narrow the observed spectrum by increasing the rate of mutation at isolated sites in the genome. In contrast, complex environments can shift the observed spectrum by defining...
Autores principales: | Flanagan, Louise M., Horton, James S., Taylor, Tiffany B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634368/ https://www.ncbi.nlm.nih.gov/pubmed/37815519 http://dx.doi.org/10.1099/mic.0.001395 |
Ejemplares similares
-
Transcription factor expression levels and environmental signals constrain transcription factor innovation
por: Shepherd, Matthew J., et al.
Publicado: (2023) -
Distribution of mutation rates challenges evolutionary predictability
por: Sun, T. Anthony, et al.
Publicado: (2023) -
Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes
por: Bové, Mona, et al.
Publicado: (2023) -
A coevolution experiment between Flavobacterium johnsoniae and Burkholderia thailandensis reveals parallel mutations that reduce antibiotic susceptibility
por: Chodkowski, John L., et al.
Publicado: (2023) -
Sustained coevolution of phage Lambda and Escherichia coli involves inner- as well as outer-membrane defences and counter-defences
por: Burmeister, Alita R., et al.
Publicado: (2021)