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Brain tuberculoma: a 52-year-old woman case report

INTRODUCTION. One of the most serious extrapulmonary type of tuberculosis that affects people under the age of 40 is brain tuberculoma. They are space-occupying masses of granulomatous tissue that result from hematogenous spread from a distant focus of tuberculous infection by Mycobacterium tubercul...

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Autores principales: Shankar, Gokul S., Nair, Sreeja, Jacob, Teena, Idikula, Mercy John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634481/
https://www.ncbi.nlm.nih.gov/pubmed/37970079
http://dx.doi.org/10.1099/acmi.0.000634.v4
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author Shankar, Gokul S.
Nair, Sreeja
Jacob, Teena
Idikula, Mercy John
author_facet Shankar, Gokul S.
Nair, Sreeja
Jacob, Teena
Idikula, Mercy John
author_sort Shankar, Gokul S.
collection PubMed
description INTRODUCTION. One of the most serious extrapulmonary type of tuberculosis that affects people under the age of 40 is brain tuberculoma. They are space-occupying masses of granulomatous tissue that result from hematogenous spread from a distant focus of tuberculous infection by Mycobacterium tuberculosis . Symptoms and radiologic features being nonspecific usually leads to misdiagnosis and mimics a variety of other infectious diseases. Anti-tubercular drugs are essential for the successful treatment of cerebral tuberculomas. CASE REPORT. The authors present a case report of a 52-year-old diabetic woman, who presented to the Emergency Department of a tertiary care hospital and was diagnosed with brain tuberculomas with a brain biopsy. Brain tuberculomas are rare and could be overlooked. Therefore, this is an important consideration in cases with higher suspicions, given the rapid decline in patient condition. CONCLUSION. Due to their rarity, ambiguous symptoms, and radiographic characteristics, intracranial tuberculomas continue to provide a clinical challenge and must always be considered in the differential diagnosis of cerebral space occupying lesions. As CSF may not yield positivity for both CBNAAT and smear examination, a brain biopsy specimen for culture should always be kept in mind for detecting tuberculoma and initiating anti-tubercular treatment at the earliest.
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spelling pubmed-106344812023-11-15 Brain tuberculoma: a 52-year-old woman case report Shankar, Gokul S. Nair, Sreeja Jacob, Teena Idikula, Mercy John Access Microbiol Case Reports INTRODUCTION. One of the most serious extrapulmonary type of tuberculosis that affects people under the age of 40 is brain tuberculoma. They are space-occupying masses of granulomatous tissue that result from hematogenous spread from a distant focus of tuberculous infection by Mycobacterium tuberculosis . Symptoms and radiologic features being nonspecific usually leads to misdiagnosis and mimics a variety of other infectious diseases. Anti-tubercular drugs are essential for the successful treatment of cerebral tuberculomas. CASE REPORT. The authors present a case report of a 52-year-old diabetic woman, who presented to the Emergency Department of a tertiary care hospital and was diagnosed with brain tuberculomas with a brain biopsy. Brain tuberculomas are rare and could be overlooked. Therefore, this is an important consideration in cases with higher suspicions, given the rapid decline in patient condition. CONCLUSION. Due to their rarity, ambiguous symptoms, and radiographic characteristics, intracranial tuberculomas continue to provide a clinical challenge and must always be considered in the differential diagnosis of cerebral space occupying lesions. As CSF may not yield positivity for both CBNAAT and smear examination, a brain biopsy specimen for culture should always be kept in mind for detecting tuberculoma and initiating anti-tubercular treatment at the earliest. Microbiology Society 2023-10-16 /pmc/articles/PMC10634481/ /pubmed/37970079 http://dx.doi.org/10.1099/acmi.0.000634.v4 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Case Reports
Shankar, Gokul S.
Nair, Sreeja
Jacob, Teena
Idikula, Mercy John
Brain tuberculoma: a 52-year-old woman case report
title Brain tuberculoma: a 52-year-old woman case report
title_full Brain tuberculoma: a 52-year-old woman case report
title_fullStr Brain tuberculoma: a 52-year-old woman case report
title_full_unstemmed Brain tuberculoma: a 52-year-old woman case report
title_short Brain tuberculoma: a 52-year-old woman case report
title_sort brain tuberculoma: a 52-year-old woman case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634481/
https://www.ncbi.nlm.nih.gov/pubmed/37970079
http://dx.doi.org/10.1099/acmi.0.000634.v4
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