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Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report

Yokenella regensburgei , belonging to the order Enterobacterales , is a rare and emerging human pathogen reported to cause both superficial and invasive infections. The 13 case reports in the literature worldwide highlight blood, bone and wound infections. To our knowledge this is the first case des...

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Autores principales: V, Annie Sheeba, Suji, Thangamani, Jayanth, Selvin Theodore, Sahni, Rani Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634489/
https://www.ncbi.nlm.nih.gov/pubmed/37970085
http://dx.doi.org/10.1099/acmi.0.000571.v4
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author V, Annie Sheeba
Suji, Thangamani
Jayanth, Selvin Theodore
Sahni, Rani Diana
author_facet V, Annie Sheeba
Suji, Thangamani
Jayanth, Selvin Theodore
Sahni, Rani Diana
author_sort V, Annie Sheeba
collection PubMed
description Yokenella regensburgei , belonging to the order Enterobacterales , is a rare and emerging human pathogen reported to cause both superficial and invasive infections. The 13 case reports in the literature worldwide highlight blood, bone and wound infections. To our knowledge this is the first case description of Y. regensburgei causing a urinary tract infection in a 69-year-old immunocompetent patient which was isolated in two separate specimens and identified using matrix-assisted laser desorption ionization time-of-flight MS. It was found to be susceptible to most antimicrobials but resistant to penicillin, amoxicillin-clavulanate, cefoxitin and colistin. Inducible chromosomal ampC resistance was demonstrated on disc approximation testing, and blaYOC-1 class C beta-lactamase, beta lactamase superfamily and MBL fold metallo-hydrolase genes were found on whole genome sequencing.
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spelling pubmed-106344892023-11-15 Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report V, Annie Sheeba Suji, Thangamani Jayanth, Selvin Theodore Sahni, Rani Diana Access Microbiol Case Reports Yokenella regensburgei , belonging to the order Enterobacterales , is a rare and emerging human pathogen reported to cause both superficial and invasive infections. The 13 case reports in the literature worldwide highlight blood, bone and wound infections. To our knowledge this is the first case description of Y. regensburgei causing a urinary tract infection in a 69-year-old immunocompetent patient which was isolated in two separate specimens and identified using matrix-assisted laser desorption ionization time-of-flight MS. It was found to be susceptible to most antimicrobials but resistant to penicillin, amoxicillin-clavulanate, cefoxitin and colistin. Inducible chromosomal ampC resistance was demonstrated on disc approximation testing, and blaYOC-1 class C beta-lactamase, beta lactamase superfamily and MBL fold metallo-hydrolase genes were found on whole genome sequencing. Microbiology Society 2023-10-17 /pmc/articles/PMC10634489/ /pubmed/37970085 http://dx.doi.org/10.1099/acmi.0.000571.v4 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Case Reports
V, Annie Sheeba
Suji, Thangamani
Jayanth, Selvin Theodore
Sahni, Rani Diana
Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title_full Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title_fullStr Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title_full_unstemmed Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title_short Yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
title_sort yokenella regensburgei urinary tract infection in an immunocompetent patient: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634489/
https://www.ncbi.nlm.nih.gov/pubmed/37970085
http://dx.doi.org/10.1099/acmi.0.000571.v4
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