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Modeling complement activation on human glomerular microvascular endothelial cells

INTRODUCTION: Atypical hemolytic uremic syndrome (aHUS) is a rare kidney disease caused by dysregulation of the complement alternative pathway. The complement dysregulation specifically leads to damage to the glomerular endothelium. To further understand aHUS pathophysiology, we validated an ex vivo...

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Detalles Bibliográficos
Autores principales:	Stevens, Kes H., Baas, Laura M., van der Velden, Thea J. A. M., Bouwmeester, Romy N., van Dillen, Niels, Dorresteijn, Eiske M., van Zuilen, Arjan D., Wetzels, Jack F. M., Michels, Marloes A. H. M., van de Kar, Nicole C. A. J., van den Heuvel, Lambertus P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634509/ https://www.ncbi.nlm.nih.gov/pubmed/37954621 http://dx.doi.org/10.3389/fimmu.2023.1206409

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