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A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet

Lactation ketoacidosis is a rare yet severe metabolic emergency that has been reported in breastfeeding mothers. Reduced carbohydrate intake during breastfeeding has been reported as a common trigger for ketoacidosis. We report the case of a 31-year-old mother without diabetes who presented with lif...

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Autores principales: Borhan, Marisa Khatijah, Vethakkan, Shireene Ratna, Sarvanandan, Tharsini, Paramasivam, Sharmila Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634626/
https://www.ncbi.nlm.nih.gov/pubmed/37954835
http://dx.doi.org/10.1210/jcemcr/luad134
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author Borhan, Marisa Khatijah
Vethakkan, Shireene Ratna
Sarvanandan, Tharsini
Paramasivam, Sharmila Sunita
author_facet Borhan, Marisa Khatijah
Vethakkan, Shireene Ratna
Sarvanandan, Tharsini
Paramasivam, Sharmila Sunita
author_sort Borhan, Marisa Khatijah
collection PubMed
description Lactation ketoacidosis is a rare yet severe metabolic emergency that has been reported in breastfeeding mothers. Reduced carbohydrate intake during breastfeeding has been reported as a common trigger for ketoacidosis. We report the case of a 31-year-old mother without diabetes who presented with life-threatening lactation ketoacidosis after following a ketogenic diet while exclusively breastfeeding her newborn baby. She was managed in the intensive care unit with dextrose and insulin infusion to reverse ketoacidosis. With prompt treatment, the patient's ketoacidosis resolved within 24 hours, and she was discharged well 3 days later. We further discuss the underlying increased metabolic demand in lactating women that puts them at risk of ketoacidosis, underlining the importance of early recognition of lactation ketoacidosis and nutritional education for lactating women.
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spelling pubmed-106346262023-11-10 A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet Borhan, Marisa Khatijah Vethakkan, Shireene Ratna Sarvanandan, Tharsini Paramasivam, Sharmila Sunita JCEM Case Rep Case Report Lactation ketoacidosis is a rare yet severe metabolic emergency that has been reported in breastfeeding mothers. Reduced carbohydrate intake during breastfeeding has been reported as a common trigger for ketoacidosis. We report the case of a 31-year-old mother without diabetes who presented with life-threatening lactation ketoacidosis after following a ketogenic diet while exclusively breastfeeding her newborn baby. She was managed in the intensive care unit with dextrose and insulin infusion to reverse ketoacidosis. With prompt treatment, the patient's ketoacidosis resolved within 24 hours, and she was discharged well 3 days later. We further discuss the underlying increased metabolic demand in lactating women that puts them at risk of ketoacidosis, underlining the importance of early recognition of lactation ketoacidosis and nutritional education for lactating women. Oxford University Press 2023-11-07 /pmc/articles/PMC10634626/ /pubmed/37954835 http://dx.doi.org/10.1210/jcemcr/luad134 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Borhan, Marisa Khatijah
Vethakkan, Shireene Ratna
Sarvanandan, Tharsini
Paramasivam, Sharmila Sunita
A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title_full A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title_fullStr A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title_full_unstemmed A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title_short A Case of Severe Lactation Ketoacidosis in a Nondiabetic Mother on a Ketogenic Diet
title_sort case of severe lactation ketoacidosis in a nondiabetic mother on a ketogenic diet
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634626/
https://www.ncbi.nlm.nih.gov/pubmed/37954835
http://dx.doi.org/10.1210/jcemcr/luad134
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