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Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure
In striated muscle, some sarcomere proteins regulate crossbridge cycling by varying the propensity of myosin heads to interact with actin. Myosin-binding protein C (MyBP-C) is bound to the myosin thick filament and is predicted to interact and stabilize myosin heads in a docked position against the...
Autores principales: | Hessel, Anthony L., Kuehn, Michel, Han, Seong-Won, Ma, Weikang, Irving, Thomas C., Momb, Brent A., Song, Taejeong, Sadayappan, Sakthivel, Linke, Wolfgang A., Palmer, Bradley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634671/ https://www.ncbi.nlm.nih.gov/pubmed/37961718 http://dx.doi.org/10.1101/2023.10.19.563160 |
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